Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ABI1
  • Mouse genes Abi1
  • Rat genes Abi1
  • Zfish genes abi1a,abi1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Abi1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	ABI1	HDA		Human	PMID:25468996
Molecular Function	GO:0005515	protein binding	ABI1	IPI	UniProtKB:P00519	Human	PMID:11418237
Molecular Function	GO:0005515	protein binding	ABI1	IPI	UniProtKB:Q9Y2A7	Human	PMID:11418237
Molecular Function	GO:0005515	protein binding	ABI1	IPI	UniProtKB:P14598	Human	PMID:12681507
Molecular Function	GO:0005515	protein binding	ABI1	IPI	UniProtKB:Q8TE67	Human	PMID:14565974
Molecular Function	GO:0005515	protein binding	ABI1	IPI	UniProtKB:Q8TE68	Human	PMID:14565974
Molecular Function	GO:0005515	protein binding	ABI1	IPI	UniProtKB:Q9H6S3	Human	PMID:14565974
Molecular Function	GO:0005515	protein binding	ABI1	IPI	UniProtKB:Q08509	Human	PMID:15289329
Molecular Function	GO:0005515	protein binding	ABI1	IPI	UniProtKB:P55160	Human	PMID:16417406
Molecular Function	GO:0005515	protein binding	ABI1	IPI	UniProtKB:P00519	Human	PMID:17101133
Molecular Function	GO:0005515	protein binding	ABI1	IPI	UniProtKB:P00519	Human	PMID:18328268
Molecular Function	GO:0005515	protein binding	ABI1	IPI	UniProtKB:O14512	Human	PMID:20598684
Molecular Function	GO:0005515	protein binding	ABI1	IPI	UniProtKB:P00519	Human	PMID:20598684
Molecular Function	GO:0005515	protein binding	ABI1	IPI	UniProtKB:P15498	Human	PMID:20598684
Molecular Function	GO:0005515	protein binding	ABI1	IPI	UniProtKB:P20936	Human	PMID:20598684
Molecular Function	GO:0005515	protein binding	ABI1	IPI	UniProtKB:P26450	Human	PMID:20598684
Molecular Function	GO:0005515	protein binding	ABI1	IPI	UniProtKB:P27986	Human	PMID:20598684
Molecular Function	GO:0005515	protein binding	ABI1	IPI	UniProtKB:P42684	Human	PMID:20598684
Molecular Function	GO:0005515	protein binding	ABI1	IPI	UniProtKB:P52735	Human	PMID:20598684
Molecular Function	GO:0005515	protein binding	ABI1	IPI	UniProtKB:Q13191	Human	PMID:20598684
Molecular Function	GO:0005515	protein binding	ABI1	IPI	UniProtKB:Q92569	Human	PMID:20598684
Molecular Function	GO:0005515	protein binding	ABI1	IPI	UniProtKB:O00555	Human	PMID:21078624
Molecular Function	GO:0005515	protein binding	ABI1	IPI	UniProtKB:Q9Y2A7	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	ABI1	IPI	UniProtKB:Q9Y2A7	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	ABI1	IPI	UniProtKB:Q08509	Human	PMID:9010225
Molecular Function	GO:0005515	protein binding	ABI1	IPI	UniProtKB:P00519	Human	PMID:9593709
Molecular Function	GO:0005515	protein binding	ABI1	IPI	UniProtKB:P02549	Human	PMID:9593709
Molecular Function	GO:0005515	protein binding	Abi1	IPI	UniProtKB:Q8BH43|UniProtKB:Q9Z207	Mouse	MGI:MGI:3771761|PMID:18044991
Molecular Function	GO:0005515	protein binding	Abi1	IPI	UniProtKB:Q08509	Mouse	MGI:MGI:5486559|PMID:15558031
Molecular Function	GO:0005515	protein binding	Abi1	IPI	UniProtKB:Q08509	Mouse	MGI:MGI:3690183|PMID:9010225
Molecular Function	GO:0005515	protein binding	Abi1	IPI	UniProtKB:Q02384	Mouse	MGI:MGI:5142386|PMID:11003655
Molecular Function	GO:0005515	protein binding	Abi1	IPI	UniProtKB:Q8BH43	Mouse	MGI:MGI:4835598|PMID:20697350
Molecular Function	GO:0005515	protein binding	Abi1	IPI	UniProtKB:Q08509	Mouse	MGI:MGI:3851270|PMID:19564905
Molecular Function	GO:0005515	protein binding	Abi1	IPI	PR:P11798	Mouse	PMID:25297099
Molecular Function	GO:0005515	protein binding	Abi1	IPI	PR:Q8BKX1	Mouse	PMID:19208628
Molecular Function	GO:0005515	protein binding	Abi1	IPI	UniProtKB:P52164	Rat	PMID:17304222|RGD:8553800
Molecular Function	GO:0005515	protein binding	Abi1	IPI	UniProtKB:Q9JLU4	Rat	PMID:17304222|RGD:8553800
Molecular Function	GO:0005515	protein binding	Abi1	IPI	RGD:1590759	Rat	PMID:20531346|RGD:11251757
Molecular Function	GO:0005515	protein binding	Abi1	IPI	RGD:71058	Rat	PMID:22102872|RGD:10002783
Molecular Function	GO:0030296	protein tyrosine kinase activator activity	Abi1	IDA		Mouse	PMID:12672821
Molecular Function	GO:0017124	SH3 domain binding	ABI1	IPI	UniProtKB:Q5T0N5	Human	PMID:19798448
Molecular Function	GO:0035591	signaling adaptor activity	ABI1	IDA		Human	PMID:17101133
Molecular Function	GO:0035591	signaling adaptor activity	Abi1	IDA		Mouse	MGI:MGI:2664008|PMID:12672821
Cellular Component	GO:0031252	cell leading edge	Abi1	IDA		Mouse	PMID:16831833
Cellular Component	GO:0031252	cell leading edge	Abi1	IDA		Mouse	PMID:19200726
Cellular Component	GO:0070062	extracellular exosome	ABI1	HDA		Human	PMID:19056867
Cellular Component	GO:0032433	filopodium tip	ABI1	IDA		Human	PMID:11516653
Cellular Component	GO:0098978	glutamatergic synapse	Abi1	EXP		Rat	PMID:17304222|RGD:8553800
Cellular Component	GO:0098978	glutamatergic synapse	Abi1	IDA		Rat	PMID:17304222|RGD:8553800
Cellular Component	GO:0098978	glutamatergic synapse	Abi1	IMP		Rat	PMID:17304222|RGD:8553800
Cellular Component	GO:0030027	lamellipodium	ABI1	IDA		Human	PMID:11516653
Cellular Component	GO:0030027	lamellipodium	ABI1	IDA		Human	PMID:17101133
Cellular Component	GO:0030027	lamellipodium	Abi1	IDA		Mouse	PMID:12672821
Cellular Component	GO:0043005	neuron projection	Abi1	IDA		Mouse	MGI:MGI:5320264|PMID:21795692
Cellular Component	GO:0014069	postsynaptic density	Abi1	IDA		Rat	PMID:17304222|RGD:8553800
Cellular Component	GO:0031209	SCAR complex	ABI1	IDA		Human	PMID:21107423
Cellular Component	GO:0031209	SCAR complex	ABI1	IDA		Human	PMID:26428302
Cellular Component	GO:0031209	SCAR complex	Abi1	IDA		Mouse	MGI:MGI:2664008|PMID:12672821
Cellular Component	GO:0031209	SCAR complex	Abi1	IDA		Mouse	MGI:MGI:6508508|PMID:26428302
Biological Process	GO:0048813	dendrite morphogenesis	Abi1	IDA		Mouse	PMID:25297099
Biological Process	GO:0072673	lamellipodium morphogenesis	Abi1	IMP		Mouse	PMID:17664349
Biological Process	GO:0035855	megakaryocyte development	Abi1	IMP		Mouse	PMID:17664349
Biological Process	GO:0061098	positive regulation of protein tyrosine kinase activity	ABI1	IDA		Human	PMID:17101133
Biological Process	GO:0099527	postsynapse to nucleus signaling pathway	Abi1	EXP		Rat	PMID:17304222|RGD:8553800
Biological Process	GO:0099527	postsynapse to nucleus signaling pathway	Abi1	IDA		Rat	PMID:17304222|RGD:8553800
Biological Process	GO:0099527	postsynapse to nucleus signaling pathway	Abi1	IEP		Rat	PMID:17304222|RGD:8553800
Biological Process	GO:0099527	postsynapse to nucleus signaling pathway	Abi1	IMP		Rat	PMID:17304222|RGD:8553800
Biological Process	GO:0001756	somitogenesis	Abi1	IMP	MGI:MGI:3578145	Mouse	PMID:15755804

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern