| Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
  | bipolar disorder | ATP1A3* | Atp1a3* | 1 model | Alliance of Genome Resources | ||
| | bipolar disorder | CAMK2A | Camk2a* | 1 model | Alliance of Genome Resources | ||
| bipolar disorder | CLOCK | Clock* | 1 model | Alliance of Genome Resources | |||
| bipolar disorder | POLG | Polg* | 1 model | Alliance of Genome Resources | |||
| major depressive disorder | CRTC1 | Crtc1* | 1 model | Alliance of Genome Resources | |||
| major depressive disorder | ADCY3 | Adcy3* | 1 model | Alliance of Genome Resources | |||
| melancholic depression | DISC1 | Disc1* | 1 model | Alliance of Genome Resources | |||
| melancholic depression | HAP1 | Hap1* | 2 models | Alliance of Genome Resources | |||
| melancholic depression | MORC1 | Morc1* | 1 model | Alliance of Genome Resources | |||
| melancholic depression | TPH2 | Tph2* | 1 model | Alliance of Genome Resources | |||
| mood disorder | POLG | Polg* | 1 model | Alliance of Genome Resources | |||
| postpartum depression | GABRD | Gabrd* | 1 model | Alliance of Genome Resources | |||
| | bipolar disorder | SLC6A4* | Slc6a4 | Alliance of Genome Resources | |||
| bipolar disorder | PPP1R1B* | Ppp1r1b | Alliance of Genome Resources | ||||
| bipolar disorder | NRG1* | Nrg1 | Alliance of Genome Resources | ||||
| bipolar disorder | NGF* | Ngf | Alliance of Genome Resources | ||||
| bipolar disorder | NCAM1* | Ncam1 | Alliance of Genome Resources | ||||
| bipolar disorder | ND1* | mt-Nd1 | Alliance of Genome Resources | ||||
| bipolar disorder | MBL2* | Mbl2 | Alliance of Genome Resources | ||||
| bipolar disorder | CHRM2* | Chrm2 | Alliance of Genome Resources | ||||
| bipolar disorder | KAT6B* | Kat6b | Alliance of Genome Resources | ||||
| bipolar disorder | IMPA2* | Impa2 | Alliance of Genome Resources | ||||
| bipolar disorder | HTR2C* | Htr2c | Alliance of Genome Resources | ||||
| bipolar disorder | GSK3B* | Gsk3b | Alliance of Genome Resources | ||||
| bipolar disorder | GRIN2B* | Grin2b | Alliance of Genome Resources | ||||
| bipolar disorder | GRIN2A* | Grin2a | Alliance of Genome Resources | ||||
| bipolar disorder | GCH1* | Gch1 | Alliance of Genome Resources | ||||
| bipolar disorder | AKT1* | Akt1 | Alliance of Genome Resources | ||||
| bipolar disorder | ANK3* | Ank3 | Alliance of Genome Resources | ||||
| bipolar disorder | AVPR1B* | Avpr1b | Alliance of Genome Resources | ||||
| bipolar disorder | BRD1* | Brd1 | Alliance of Genome Resources | ||||
| bipolar disorder | CCL2*, CCL13 | Ccl2, Ccl12 | Alliance of Genome Resources | ||||
| bipolar disorder | GAD1* | Gad1 | Alliance of Genome Resources | ||||
| bipolar disorder | GABRA5* | Gabra5 | Alliance of Genome Resources | ||||
| bipolar disorder | GABRA3* | Gabra3 | Alliance of Genome Resources | ||||
| bipolar disorder | DISC1* | Disc1 | Alliance of Genome Resources | ||||
| bipolar disorder | DDC* | Ddc | Alliance of Genome Resources | ||||
| bipolar disorder | DAOA* | ||||||
| bipolar disorder | COMT* | Comt | Alliance of Genome Resources | ||||
| bipolar disorder | SYNE1* | Syne1 | Alliance of Genome Resources | ||||
| bipolar disorder | SSTR5* | Sstr5 | Alliance of Genome Resources | ||||
| bipolar disorder | SLC18A1* | Slc18a1 | Alliance of Genome Resources | ||||
| depressive disorder | NTS* | Nts | Alliance of Genome Resources | ||||
| depressive disorder | CHRNB3* | Chrnb3 | Alliance of Genome Resources | ||||
| depressive disorder | CRHBP* | Crhbp | Alliance of Genome Resources | ||||
| depressive disorder | DRD2* | Drd2 | Alliance of Genome Resources | ||||
| depressive disorder | GABRA5* | Gabra5 | Alliance of Genome Resources | ||||
| depressive disorder | GATA1* | Gata1 | Alliance of Genome Resources | ||||
| depressive disorder | GATA2* | Gata2 | Alliance of Genome Resources | ||||
| depressive disorder | GNB3* | Gnb3 | Alliance of Genome Resources | ||||
| depressive disorder | GPX1* | Gpx1 | Alliance of Genome Resources | ||||
| depressive disorder | HTR1A* | Htr1a | Alliance of Genome Resources | ||||
| depressive disorder | HTR3B* | Htr3b | Alliance of Genome Resources | ||||
| depressive disorder | IL1RN* | Il1rn | Alliance of Genome Resources | ||||
| depressive disorder | IL6* | Il6 | Alliance of Genome Resources | ||||
| depressive disorder | NGFR* | Ngfr | Alliance of Genome Resources | ||||
| depressive disorder | NPPC* | Nppc | Alliance of Genome Resources | ||||
| depressive disorder | NPY* | Npy | Alliance of Genome Resources | ||||
| depressive disorder | OPRK1* | Oprk1 | Alliance of Genome Resources | ||||
| depressive disorder | PANX1* | Panx1 | Alliance of Genome Resources | ||||
| depressive disorder | SLC5A7* | Slc5a7 | Alliance of Genome Resources | ||||
| depressive disorder | SLC6A4* | Slc6a4 | Alliance of Genome Resources | ||||
| depressive disorder | STK33* | Stk33 | Alliance of Genome Resources | ||||
| depressive disorder | TPH1* | Tph1 | Alliance of Genome Resources | ||||
| depressive disorder | XIRP2* | Xirp2 | Alliance of Genome Resources | ||||
| major depressive disorder | TPH2* | Tph2 | Alliance of Genome Resources | ||||
| major depressive disorder | SLC6A4* | Slc6a4 | Alliance of Genome Resources | ||||
| major depressive disorder | PDYN* | Pdyn | Alliance of Genome Resources | ||||
| major depressive disorder | NTRK2* | Ntrk2 | Alliance of Genome Resources | ||||
| major depressive disorder | NR3C1* | Nr3c1 | Alliance of Genome Resources | ||||
| major depressive disorder | MED12* | Med12 | Alliance of Genome Resources | ||||
| major depressive disorder | MC1R* | Mc1r | Alliance of Genome Resources | ||||
| major depressive disorder | IL10* | Il10 | Alliance of Genome Resources | ||||
| major depressive disorder | IL6* | Il6 | Alliance of Genome Resources | ||||
| major depressive disorder | HTR2A* | Htr2a | Alliance of Genome Resources | ||||
| major depressive disorder | HSPA1L* | Hspa1l | Alliance of Genome Resources | ||||
| major depressive disorder | HSPA1A*, HSPA1B | Hspa1a, Hspa1b | Alliance of Genome Resources | ||||
| major depressive disorder | FOXP2* | Foxp2 | Alliance of Genome Resources | ||||
| major depressive disorder | FKBP5* | Fkbp5 | Alliance of Genome Resources | ||||
| major depressive disorder | DISC1* | Disc1 | Alliance of Genome Resources | ||||
| major depressive disorder | CYP2D6*, CYP2D7 | Cyp2d9, Cyp2d10, Cyp2d11, Cyp2d12, Cyp2d22, Cyp2d26, Cyp2d34, Cyp2d40 | Alliance of Genome Resources | ||||
| major depressive disorder | CTNND2* | Ctnnd2 | Alliance of Genome Resources | ||||
| major depressive disorder | CNTNAP2* | Cntnap2 | Alliance of Genome Resources | ||||
| major depressive disorder | CHRM2* | Chrm2 | Alliance of Genome Resources | ||||
| mood disorder | AVPR1B* | Avpr1b | Alliance of Genome Resources | ||||
| postpartum depression | TPH1* | Tph1 | Alliance of Genome Resources | ||||
Excel File
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Transgenes and other genome features developed in mice to model this disease.
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| Disease Term | Transgenes and Other Genome Features | Mouse Models | |
| bipolar disorder | Tg(Camk2a-Polg*D181A)BTkato | 1 model | |
| melancholic depression | Tg(Syn1-ADCY7)11004Btab | 1 model | |
| mood disorder | Tg(Camk2a-Polg*D181A)BTkato | 1 model | |