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Gene Expression Data
Assay Details
Assay
Reference: J:348078 Nie X, et al., Piezo1 and Piezo2 collectively regulate jawbone development. Development. 2024 May 1;151(9):dev202386
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8288996
Gene symbol: Piezo1
Gene name: piezo-type mechanosensitive ion channel component 1
Antibody: anti-PIEZO1 (2-10) - MA5-32876
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1B: embryonic day 13.5 (more )
Note: Double labeled: green - Piezo1; red - Alpl (assay MGI:8288998).
Structure Cell Type Level Pattern Image Note
TS21: mandible preosteoblast Strong 1B merge , 1B Piezo1 Co-localization with Alpl in the mandibular arches.
Specimen 1D: embryonic day 14.5 (more )
Note: Double labeled: green - Piezo1; red - Alpl (assay MGI:8288998).
Structure Cell Type Level Pattern Image Note
TS22: mandible preosteoblast Strong 1D Piezo1 , 1D merge Co-localization with Alpl in the mandibular arches.
Specimen 1F: embryonic day 16.5 (more )
Note: Double labeled: green - Piezo1; red - Piezo2 (assay MGI:8288999).
Structure Level Pattern Image Note
TS24: mandible Strong 1F Piezo1 , 1F merge Co-localization with Piezo2 in the mandibular arches.
Specimen 1H: postnatal day 0 (more )
Note: Double labeled: green - Piezo1; red - Piezo2 (assay MGI:8288999).
Structure Level Pattern Image Note
TS27: mandible Strong 1H merge , 1H Piezo1 Co-localization with Piezo2 in the mandibular arches.
Specimen 1J: postnatal week 3; Piezo1tm2.1Apat/Piezo1tm2.1Apat (more )
Note: Double labeled: green - Piezo1; red - Alpl (assay MGI:8288998).
Structure Cell Type Level Pattern Image Note
TS28: mandible alveolar process osteoblast Present 1J merge , 1J Piezo1 Co-localization with Alpl.
TS28: periosteum osteoblast Present 1J merge , 1J Piezo1 Co-localization with Alpl.
TS28: periodontal ligament Present 1J merge , 1J Piezo1
Specimen 1L: postnatal week 3; E2f1Tg(Wnt1-cre)2Sor/E2f1+, Piezo1tm2.1Apat/Piezo1tm2.1Apat (more )
Note: Conditional mutant. Double labeled: green - Piezo1; red - Alpl (assay MGI:8288998).
Structure Level Pattern Image Note
TS28: mandible alveolar process Absent 1L Piezo1 , 1L merge
TS28: periodontal ligament Absent 1L Piezo1 , 1L merge
TS28: periosteum Absent 1L Piezo1 , 1L merge
Specimen 2N: postnatal adult; Piezo1tm2.1Apat/Piezo1tm2.1Apat (more )
Note: Double labeled: green - Piezo1; red - Piezo2 (assay MGI:8288999).
Structure Level Pattern Image Note
TS28: mandible alveolar process Present 2N Piezo1 , 2N merge
TS28: periodontal ligament Present 2N Piezo1 , 2N merge
TS28: periosteum Present 2N Piezo1 , 2N merge
Specimen 2O: postnatal adult; E2f1Tg(Wnt1-cre)2Sor/E2f1+, Piezo1tm2.1Apat/Piezo1tm2.1Apat (more )
Note: Conditional mutant. Double labeled: green - Piezo1; red - Piezo2 (assay MGI:8288999).
Structure Level Pattern Image Note
TS28: mandible alveolar process Absent 2O Piezo1 , 2O merge
TS28: periodontal ligament Absent 2O Piezo1 , 2O merge
TS28: periosteum Absent 2O Piezo1 , 2O merge
Specimen S1A: embryonic day 12.5 (more )
Note: Double labeled: green - Piezo1; red - Alpl (assay MGI:8288998).
Structure Cell Type Level Pattern Image Note
TS20: jaw bone preosteoblast Present Regionally restricted S1A Co-localization with Alpl in the mandibular arches.
Specimen S1B: embryonic day 13.5 (more )
Note: Double labeled: green - Piezo1; red - Alpl (assay MGI:8288998).
Structure Cell Type Level Pattern Image Note
TS21: mandible preosteoblast Strong S1B Co-localization with Alpl in the mandibular arches.
Specimen S1C: embryonic day 14.5 (more )
Note: Double labeled: green - Piezo1; red - Alpl (assay MGI:8288998).
Structure Cell Type Level Pattern Image Note
TS22: mandible preosteoblast Strong S1C Co-localization with Alpl in the mandibular arches.
Specimen S1D: postnatal day 0 (more )
Note: Double labeled: green - Piezo1; red - Alpl (assay MGI:8288998).
Structure Cell Type Level Pattern Image Note
TS27: mandible osteoblast Strong S1D Co-localization with Alpl in the mandibular arches.
Specimen S1E/F: postnatal week 3 (more )
Note: Double labeled: green - Piezo1; red - Piezo2 (assay MGI:8288999).
Structure Level Pattern Image Note
TS28: mandible alveolar process Present S1F , S1E
TS28: periodontal ligament Present S1F , S1E
TS28: periosteum Present S1F , S1E
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/14/2026
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