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Gene Expression Data
Assay Details
Assay
Reference: J:348078 Nie X, et al., Piezo1 and Piezo2 collectively regulate jawbone development. Development. 2024 May 1;151(9):dev202386
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8288999
Gene symbol: Piezo2
Gene name: piezo-type mechanosensitive ion channel component 2
Antibody: anti-Piezo2
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen 1F: embryonic day 16.5 (more )
Note: Double labeled: red - Piezo2; green - Piezo1 (assay MGI:8288996).
Structure Level Pattern Image Note
TS24: mandible Present 1F merge , 1F Piezo2 Co-localization with Piezo1 in the mandibular arches.

Specimen 1H: postnatal day 0 (more )
Note: Double labeled: red - Piezo2; green - Piezo1 (assay MGI:8288996).
Structure Level Pattern Image Note
TS27: mandible Present 1H merge , 1H Piezo2 Co-localization with Piezo2 in the mandibular arches.

Specimen 2N: postnatal adult; Piezo1tm2.1Apat/Piezo1tm2.1Apat (more )
Note: Double labeled: red - Piezo2; green - Piezo1 (assay MGI:8288996).
Structure Level Pattern Image Note
TS28: mandible alveolar process Present 2N Piezo2 , 2N merge Co-localization with Piezo1.
TS28: periosteum Present 2N Piezo2 , 2N merge Co-localization with Piezo1.

Specimen 2O: postnatal adult; E2f1Tg(Wnt1-cre)2Sor/E2f1+, Piezo1tm2.1Apat/Piezo1tm2.1Apat (more )
Note: Conditional mutant. Double labeled: red - Piezo2; green - Piezo1 (assay MGI:8288996).
Structure Level Pattern Image Note
TS28: mandible alveolar process Present 2O merge , 2O Piezo2 More robust expression compared with the control, as indicated by an increase in the number of Piezo2+ cells in bone-lining cells.
TS28: periosteum Present 2O merge , 2O Piezo2 More robust expression compared with the control, as indicated by an increase in the number of Piezo2+ cells in bone-lining cells.

Specimen S1E/G: postnatal week 3 (more )
Note: Double labeled: red - Piezo2; green - Piezo1 (assay MGI:8288996).
Structure Level Pattern Image Note
TS28: mandible alveolar process Present S1G , S1E Co-localization with Piezo1.
TS28: periosteum Present S1G , S1E Co-localization with Piezo1.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/14/2026
MGI 6.24
The Jackson Laboratory