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Gene Expression Data
Assay Details
Assay
Reference: J:353621 Patel VN, et al., Specific 3-O-sulfated heparan sulfate domains regulate salivary gland basement membrane metabolism and epithelial differentiation. Nat Commun. 2024 Aug 31;15(1):7584
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7863420
Gene symbol: Aqp5
Gene name: aquaporin 5
Results
Specimen 4e WT: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: submandibular gland acinar cell Present Regionally restricted 4e WT Aqp5 Staining for acinar apical water channel.
Structure Cell Type Level Pattern Image Note
TS28: submandibular gland acinar cell Weak Regionally restricted 4e DKO Aqp5 Apical staining in the DKO was disrupted.
Specimen 6b WT: embryonic day 16.5 (more )
Note: Triple labeled: yellow - Aqp5; green - Acta2 (assay MGI:7863326); magenta - Hspg2 (assay MGI:7863665).
Structure Cell Type Level Pattern Image Note
TS24: submandibular gland acinar cell Present Regionally restricted 6b WT Expression was detected in the acinar apical membranes.
Specimen 6b DKO: embryonic day 16.5; Hs3st3a1tm1(KOMP)Vlcg/Hs3st3a1tm1(KOMP)Vlcg, Hs3st3b1tm1(KOMP)Vlcg/Hs3st3b1tm1(KOMP)Vlcg (more )
Note: Triple labeled: yellow - Aqp5; green - Acta2 (assay MGI:7863326); magenta - Hspg2 (assay MGI:7863665).
Structure Cell Type Level Pattern Image Note
TS24: submandibular gland acinar cell Present Regionally restricted 6b DKO Expression in the DKO acinar apical membranes was similar to the WT.
Specimen 6d WT: postnatal day 2 (more )
Note: Double labeled: magenta - Aqp5; green - Acta2 (assay MGI:7863326).
Structure Cell Type Level Pattern Image Note
TS27: submandibular gland acinar cell Present Regionally restricted 6d WT Expression was detected in the acinar apical membranes.
Specimen 6d DKO: postnatal day 2; Hs3st3a1tm1(KOMP)Vlcg/Hs3st3a1tm1(KOMP)Vlcg, Hs3st3b1tm1(KOMP)Vlcg/Hs3st3b1tm1(KOMP)Vlcg (more )
Note: Double labeled: magenta - Aqp5; green - Acta2 (assay MGI:7863326).
Structure Cell Type Level Pattern Image Note
TS27: submandibular gland acinar cell Present Regionally restricted 6d DKO Expression was reduced in the DKO acinar apical membranes.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory