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Gene Expression Data
Assay Details
Assay
Reference: J:353621 Patel VN, et al., Specific 3-O-sulfated heparan sulfate domains regulate salivary gland basement membrane metabolism and epithelial differentiation. Nat Commun. 2024 Aug 31;15(1):7584
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7863326
Gene symbol: Acta2
Gene name: actin alpha 2, smooth muscle, aorta
Results
Specimen 2d WT right: postnatal adult (more )
Note: Double labeled: green - Acta2; magenta - Egf (assay MGI:7863327).
Structure Cell Type Level Pattern Image Note
TS28: submandibular gland epithelium myoepithelial cell Present 2d WT right
Specimen 2d DKO right: postnatal adult; Hs3st3a1tm1(KOMP)Vlcg/Hs3st3a1tm1(KOMP)Vlcg, Hs3st3b1tm1(KOMP)Vlcg/Hs3st3b1tm1(KOMP)Vlcg (more )
Note: Double labeled: green - Acta2; magenta - Egf (assay MGI:7863327).
Structure Cell Type Level Pattern Image Note
TS28: submandibular gland epithelium myoepithelial cell Present 2d DKO right A reduction in myoepithelial cells was noted in the DKO compared with wild type.
Specimen 6b WT: embryonic day 16.5 (more )
Note: Triple labeled: green - Acta2; yellow - Aqp5 (assay MGI:7863420); magenta - Hspg2 (assay MGI:7863665).
Structure Cell Type Level Pattern Image Note
TS24: submandibular gland myoepithelial cell Present 6b WT
Specimen 6b DKO: embryonic day 16.5; Hs3st3a1tm1(KOMP)Vlcg/Hs3st3a1tm1(KOMP)Vlcg, Hs3st3b1tm1(KOMP)Vlcg/Hs3st3b1tm1(KOMP)Vlcg (more )
Note: Triple labeled: green - Acta2; yellow - Aqp5 (assay MGI:7863420); magenta - Hspg2 (assay MGI:7863665).
Structure Cell Type Level Pattern Image Note
TS24: submandibular gland myoepithelial cell Present 6b DKO Expression in the DKO was similar to WT.
Specimen 6d WT: postnatal day 2 (more )
Note: Double labeled: green - Acta2; magenta - Aqp5 (assay MGI:7863420).
Structure Cell Type Level Pattern Image Note
TS27: submandibular gland myoepithelial cell Present 6d WT
Specimen 6d DKO: postnatal day 2; Hs3st3a1tm1(KOMP)Vlcg/Hs3st3a1tm1(KOMP)Vlcg, Hs3st3b1tm1(KOMP)Vlcg/Hs3st3b1tm1(KOMP)Vlcg (more )
Note: Double labeled: green - Acta2; magenta - Aqp5 (assay MGI:7863420).
Structure Cell Type Level Pattern Image Note
TS27: submandibular gland myoepithelial cell Present 6d DKO Expression was reduced in the DKO at P2.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory