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Gene Expression Data
Assay Details
Assay
Reference: J:95889 Wines-Samuelson M, et al., Role of presenilin-1 in cortical lamination and survival of Cajal-Retzius neurons. Dev Biol. 2005 Jan 15;277(2):332-46
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7571571
Gene symbol: Nes
Gene name: nestin
Antibody: clone RC2
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 4A: embryonic day 11.5; Psen1tm2Shn/Psen1+ (more )
Structure Cell Type Level Pattern Image Note
TS19: telencephalon forebrain radial glial cell Present 4A
Specimen 4B: embryonic day 11.5; Psen1tm2Shn/Psen1tm2.1Shn, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS19: telencephalon forebrain radial glial cell Present 4B Expression in the radial glia of the telencephalon in the conditional knockout was comparable to the control.
Specimen 4C: embryonic day 12.5; Psen1tm2Shn/Psen1+ (more )
Structure Cell Type Level Pattern Image Note
TS20: telencephalon forebrain radial glial cell Present 4C
Specimen 4D: embryonic day 12.5; Psen1tm2Shn/Psen1tm2.1Shn, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS20: telencephalon forebrain radial glial cell Present 4D Expression in the radial glia of the telencephalon in the conditional knockout was comparable to the control.
Specimen 4E: embryonic day 13.5; Psen1tm2Shn/Psen1+ (more )
Structure Cell Type Level Pattern Image Note
TS21: telencephalon forebrain radial glial cell Present 4E
Specimen 4F: embryonic day 13.5; Psen1tm2Shn/Psen1tm2.1Shn, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS21: telencephalon forebrain radial glial cell Weak 4F Expression in the radial glia of the telencephalon in the conditional knockout was reduced compared to the control.
Specimen 4G: embryonic day 15.5; Psen1tm2Shn/Psen1+ (more )
Structure Cell Type Level Pattern Image Note
TS23: telencephalon forebrain radial glial cell Present 4G
Specimen 4H: embryonic day 15.5; Psen1tm2Shn/Psen1tm2.1Shn, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS23: telencephalon forebrain radial glial cell Weak Non-Uniform 4H At E15.5, expression was further diminished in the conditional knockout telencephalon, with shorter glial processes extending toward the pial membrane and more intense immunostaining near the lateral ventricle.
Specimen 4I: embryonic day 17.5; Psen1tm2Shn/Psen1+ (more )
Structure Cell Type Level Pattern Image Note
TS25: telencephalon forebrain radial glial cell Present 4I
Specimen 4J: embryonic day 17.5; Psen1tm2Shn/Psen1tm2.1Shn, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS25: telencephalon forebrain radial glial cell Weak 4J Expression was markedly reduced in the conditional knockout compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/06/2026
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