Results
|
Specimen
2 E10.5 YFP/+ (upper):
embryonic day 10.5; Ptf1atm2.1Mgn/Ptf1a +
(more )
Specimen
2 E10.5 YFP/+ (upper):
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6
|
Mutant Allele(s):
|
Ptf1atm2.1Mgn/Ptf1a+
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
2 E10.5 YFP/+ (lower):
embryonic day 10.5; Ptf1atm2.1Mgn/Ptf1a +
(more )
Specimen
2 E10.5 YFP/+ (lower):
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6
|
Mutant Allele(s):
|
Ptf1atm2.1Mgn/Ptf1a+
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
2 E10.5 YFP/YFP (upper):
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6
|
Mutant Allele(s):
|
Ptf1atm2.1Mgn/Ptf1atm2.1Mgn
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
2 E10.5 YFP/YFP (lower):
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6
|
Mutant Allele(s):
|
Ptf1atm2.1Mgn/Ptf1atm2.1Mgn
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
2 E11.5 YFP/+ (upper):
embryonic day 11.5; Ptf1atm2.1Mgn/Ptf1a +
(more )
Specimen
2 E11.5 YFP/+ (upper):
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6
|
Mutant Allele(s):
|
Ptf1atm2.1Mgn/Ptf1a+
|
Age:
|
embryonic day 11.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
2 E11.5 YFP/+ (lower):
embryonic day 11.5; Ptf1atm2.1Mgn/Ptf1a +
(more )
Specimen
2 E11.5 YFP/+ (lower):
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6
|
Mutant Allele(s):
|
Ptf1atm2.1Mgn/Ptf1a+
|
Age:
|
embryonic day 11.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
2 E11.5 YFP/YFP (upper):
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6
|
Mutant Allele(s):
|
Ptf1atm2.1Mgn/Ptf1atm2.1Mgn
|
Age:
|
embryonic day 11.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
2 E11.5 YFP/YFP (lower):
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6
|
Mutant Allele(s):
|
Ptf1atm2.1Mgn/Ptf1atm2.1Mgn
|
Age:
|
embryonic day 11.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
2 E12.5 YFP/+:
embryonic day 12.5; Ptf1atm2.1Mgn/Ptf1a +
(more )
Specimen
2 E12.5 YFP/+:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6
|
Mutant Allele(s):
|
Ptf1atm2.1Mgn/Ptf1a+
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
2 E12.5 YFP/YFP:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6
|
Mutant Allele(s):
|
Ptf1atm2.1Mgn/Ptf1atm2.1Mgn
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: pancreas |
Present |
Regionally restricted |
2_E12.5 YFP/YFP
|
Expression in ventral pancreatic remnant disappears by E12.5.
|
Specimen
2 E13.5 YFP/+ (upper):
embryonic day 13.5; Ptf1atm2.1Mgn/Ptf1a +
(more )
Specimen
2 E13.5 YFP/+ (upper):
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6
|
Mutant Allele(s):
|
Ptf1atm2.1Mgn/Ptf1a+
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
2 E13.5 YFP/+ (lower):
embryonic day 13.5; Ptf1atm2.1Mgn/Ptf1a +
(more )
Specimen
2 E13.5 YFP/+ (lower):
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6
|
Mutant Allele(s):
|
Ptf1atm2.1Mgn/Ptf1a+
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
2 E13.5 YFP/YFP (upper):
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6
|
Mutant Allele(s):
|
Ptf1atm2.1Mgn/Ptf1atm2.1Mgn
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
2 E13.5 YFP/YFP (lower):
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6
|
Mutant Allele(s):
|
Ptf1atm2.1Mgn/Ptf1atm2.1Mgn
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
2 E15.5 YFP/+:
embryonic day 15.5; Ptf1atm2.1Mgn/Ptf1a +
(more )
Specimen
2 E15.5 YFP/+:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6
|
Mutant Allele(s):
|
Ptf1atm2.1Mgn/Ptf1a+
|
Age:
|
embryonic day 15.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS23: pancreatic acinus |
Very strong |
Regionally restricted |
2_E15.5 YFP/+
|
Intensity of expression increased further, corresponding with expansion of exocrine cells.
|
Specimen
2 E15.5 YFP/YFP:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6
|
Mutant Allele(s):
|
Ptf1atm2.1Mgn/Ptf1atm2.1Mgn
|
Age:
|
embryonic day 15.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
adult not shown:
postnatal adult; Ptf1atm2.1Mgn/Ptf1a +
(more )
Specimen
adult not shown:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6
|
Mutant Allele(s):
|
Ptf1atm2.1Mgn/Ptf1a+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
Not Specified
|
Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: pancreas |
Strong |
Widespread |
|
Authors report pancreas-wide expression similar to that observed in late embryogenesis.
|
Specimen
3I:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6
|
Mutant Allele(s):
|
Pdx1tm2Cvw/Pdx1tm2Cvw Ptf1atm2.1Mgn/Ptf1a+
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
3J:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6
|
Mutant Allele(s):
|
Pdx1tm2Cvw/Pdx1tm2Cvw Ptf1atm2.1Mgn/Ptf1a+
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: pancreas |
Present |
Regionally restricted |
3J
|
Expression only in dorsal pancreatic remnant from E10.5 to E12.5.
|
Specimen
3K:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6
|
Mutant Allele(s):
|
Pdx1tm2Cvw/Pdx1tm2Cvw Ptf1atm2.1Mgn/Ptf1atm2.1Mgn
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
3L:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6
|
Mutant Allele(s):
|
Pdx1tm2Cvw/Pdx1tm2Cvw Ptf1atm2.1Mgn/Ptf1atm2.1Mgn
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: pancreas |
Present |
Regionally restricted |
3L
|
Expression only in dorsal pancreatic remnant from E10.5 to E12.5.
|
Specimen
E13.5 LacZko/LacZko;YFP/+ not shown:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6
|
Mutant Allele(s):
|
Pdx1tm2Cvw/Pdx1tm2Cvw Ptf1atm2.1Mgn/Ptf1a+
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
Not Specified
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
E13.5 LacZko/LacZko;YFP/YFP not shown:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6
|
Mutant Allele(s):
|
Pdx1tm2Cvw/Pdx1tm2Cvw Ptf1atm2.1Mgn/Ptf1atm2.1Mgn
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
Not Specified
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
5A YFP (upper):
embryonic day 10.5; Ptf1atm2.1Mgn/Ptf1a +
(more )
Note: Triple labeled: green - Ptf1a reporter; blue - Pdx1 (assay MGI:6695727); red - Gcg (assay MGI:6695729).
Specimen
5A YFP (upper):
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6
|
Mutant Allele(s):
|
Ptf1atm2.1Mgn/Ptf1a+
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Triple labeled: green - Ptf1a reporter; blue - Pdx1 (assay MGI:6695727); red - Gcg (assay MGI:6695729).
|
Specimen
5A YFP (lower):
embryonic day 10.5; Ptf1atm2.1Mgn/Ptf1a +
(more )
Note: Triple labeled: green - Ptf1a reporter; blue - Pdx1 (assay MGI:6695727); red - Gcg (assay MGI:6695729).
Specimen
5A YFP (lower):
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6
|
Mutant Allele(s):
|
Ptf1atm2.1Mgn/Ptf1a+
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Triple labeled: green - Ptf1a reporter; blue - Pdx1 (assay MGI:6695727); red - Gcg (assay MGI:6695729).
|
Specimen
5C E13.5:
embryonic day 13.5; Ptf1atm2.1Mgn/Ptf1a +
(more )
Note: Triple labeled: green - Ptf1a reporter; blue - Pdx1 (assay MGI:6695727); red - Neurog3 (assay MGI:6695730).
Specimen
5C E13.5:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6
|
Mutant Allele(s):
|
Ptf1atm2.1Mgn/Ptf1a+
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Triple labeled: green - Ptf1a reporter; blue - Pdx1 (assay MGI:6695727); red - Neurog3 (assay MGI:6695730).
|
Specimen
5C E15.5:
embryonic day 15.5; Ptf1atm2.1Mgn/Ptf1a +
(more )
Note: Triple labeled: green - Ptf1a reporter; blue - Pdx1 (assay MGI:6695727); red - Neurog3 (assay MGI:6695730).
Specimen
5C E15.5:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6
|
Mutant Allele(s):
|
Ptf1atm2.1Mgn/Ptf1a+
|
Age:
|
embryonic day 15.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Triple labeled: green - Ptf1a reporter; blue - Pdx1 (assay MGI:6695727); red - Neurog3 (assay MGI:6695730).
|
Specimen
5D (middle):
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6
|
Mutant Allele(s):
|
Ptf1atm2.1Mgn/Ptf1atm2.1Mgn
|
Age:
|
embryonic day 11.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Triple labeled: green - Ptf1a reporter; blue - Pdx1 (assay MGI:6695727); red - Neurog3 (assay MGI:6695730).
|
Specimen
5D (right):
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6
|
Mutant Allele(s):
|
Ptf1atm2.1Mgn/Ptf1atm2.1Mgn
|
Age:
|
embryonic day 11.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Double labeled: green - Ptf1a reporter; blue - Pdx1 (assay MGI:6695727).
|
Specimen
S1 YFP E9.5:
embryonic day 9.5; Ptf1atm2.1Mgn/Ptf1a +
(more )
Note: Double labeled: green - Ptf1a reporter; red - Ptf1a protein (assay MGI:6695726).
Specimen
S1 YFP E9.5:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6
|
Mutant Allele(s):
|
Ptf1atm2.1Mgn/Ptf1a+
|
Age:
|
embryonic day 9.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Double labeled: green - Ptf1a reporter; red - Ptf1a protein (assay MGI:6695726).
|
Specimen
S1 YFP E10.5:
embryonic day 10.5; Ptf1atm2.1Mgn/Ptf1a +
(more )
Note: Double labeled: green - Ptf1a reporter; red - Ptf1a protein (assay MGI:6695726).
Specimen
S1 YFP E10.5:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6
|
Mutant Allele(s):
|
Ptf1atm2.1Mgn/Ptf1a+
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Double labeled: green - Ptf1a reporter; red - Ptf1a protein (assay MGI:6695726).
|
Specimen
S1 YFP E11.5:
embryonic day 11.5; Ptf1atm2.1Mgn/Ptf1a +
(more )
Note: Double labeled: green - Ptf1a reporter; red - Ptf1a protein (assay MGI:6695726).
Specimen
S1 YFP E11.5:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6
|
Mutant Allele(s):
|
Ptf1atm2.1Mgn/Ptf1a+
|
Age:
|
embryonic day 11.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Double labeled: green - Ptf1a reporter; red - Ptf1a protein (assay MGI:6695726).
|
Specimen
S1 YFP E12.5:
embryonic day 12.5; Ptf1atm2.1Mgn/Ptf1a +
(more )
Note: Double labeled: green - Ptf1a reporter; red - Ptf1a protein (assay MGI:6695726).
Specimen
S1 YFP E12.5:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6
|
Mutant Allele(s):
|
Ptf1atm2.1Mgn/Ptf1a+
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Double labeled: green - Ptf1a reporter; red - Ptf1a protein (assay MGI:6695726).
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: pancreas |
Strong |
Regionally restricted |
S1_E12.5 Merge
,
S1_E12.5 YFP
|
Intense expression co-localizing with that of Ptf1a, except for some weaker expression towards central part of pancreas epithelium.
|
Specimen
S1 YFP E13.5:
embryonic day 13.5; Ptf1atm2.1Mgn/Ptf1a +
(more )
Note: Double labeled: green - Ptf1a reporter; red - Ptf1a protein (assay MGI:6695726).
Specimen
S1 YFP E13.5:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6
|
Mutant Allele(s):
|
Ptf1atm2.1Mgn/Ptf1a+
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Double labeled: green - Ptf1a reporter; red - Ptf1a protein (assay MGI:6695726).
|
Specimen
S1 YFP E15.5:
embryonic day 15.5; Ptf1atm2.1Mgn/Ptf1a +
(more )
Note: Double labeled: green - Ptf1a reporter; red - Ptf1a protein (assay MGI:6695726).
Specimen
S1 YFP E15.5:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6
|
Mutant Allele(s):
|
Ptf1atm2.1Mgn/Ptf1a+
|
Age:
|
embryonic day 15.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Double labeled: green - Ptf1a reporter; red - Ptf1a protein (assay MGI:6695726).
|
Specimen
S2A YFP:
embryonic day 12.5; Ptf1atm2.1Mgn/Ptf1a +
(more )
Note: Triple labeled: green - Ptf1a reporter; blue - Pdx1 (assay MGI:6695727); red - Ptf1a protein (assay MGI:6695726).
Specimen
S2A YFP:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6
|
Mutant Allele(s):
|
Ptf1atm2.1Mgn/Ptf1a+
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Triple labeled: green - Ptf1a reporter; blue - Pdx1 (assay MGI:6695727); red - Ptf1a protein (assay MGI:6695726).
|
Specimen
S2B YFP:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6
|
Mutant Allele(s):
|
Ptf1atm2.1Mgn/Ptf1atm2.1Mgn
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Triple labeled: green - Ptf1a reporter; blue - Pdx1 (assay MGI:6695727); red - Ptf1a protein (assay MGI:6695726).
|
|