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Gene Expression Data
Assay Details
Assay
Reference: J:186556 Trask MC, et al., Yin-Yang1 is required for epithelial-to-mesenchymal transition and regulation of Nodal signaling during mammalian gastrulation. Dev Biol. 2012 Aug 15;368(2):273-82
Assay type: RNA in situ
MGI Accession ID: MGI:6446824
Gene symbol: Nodal
Gene name: nodal growth differentiation factor
Probe: Nodal probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3A: embryonic day 7.0 (more )
Note: littermate control; exact genotype not specified
Structure Level Pattern Image Note
TS10: primitive streak Present Regionally restricted 3A Expression is seen in the anterior streak.
Specimen 3B: embryonic day 7.5 (more )
Note: littermate control; exact genotype not specified
Structure Level Pattern Image Note
TS11: node Present 3B
Specimen 3B': embryonic day 7.5 (more )
Note: littermate control; exact genotype not specified
Structure Level Pattern Image Note
TS11: primitive streak Absent 3B' Expression is restricted to the node at this age.
Specimen 3E: embryonic day 7.0; Yy1tm1Yshi/Yy1tm2.1Yshi, Edil3Tg(Sox2-cre)1Amc/Edil3+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS10: embryo Present Regionally restricted 3E There is ectopic expression throughout the posterior half of the epiblast.
Specimen 3F: embryonic day 7.5; Yy1tm1Yshi/Yy1tm2.1Yshi, Edil3Tg(Sox2-cre)1Amc/Edil3+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS11: embryo Present Regionally restricted 3F There is ectopic expression throughout the posterior half of the epiblast and in streak derivatives.
Specimen 3F': embryonic day 7.5; Yy1tm1Yshi/Yy1tm2.1Yshi, Edil3Tg(Sox2-cre)1Amc/Edil3+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS11: embryo Present Regionally restricted 3F' There is ectopic expression throughout the posterior half of the epiblast and in streak derivatives.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory