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Gene Expression Data
Assay Details
Assay
Reference: J:290315 Cheong A, et al., Nuclear-encoded mitochondrial ribosomal proteins are required to initiate gastrulation. Development. 2020 May 26;147(10):dev188714
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6445567
Gene symbol: Cdh1
Gene name: cadherin 1
Antibody: Anti-E-Cadherin (610181; Clone 36)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 3A: embryonic day 7.5 (more )
Note: Littermate control; embryo is either +/+ or +/-. Double labeled: green - Cdh1; red - Pou5f1 (assay MGI:6445528).
Structure Level Pattern Image Note
TS11: conceptus Present 3A'' , 3A Expression is seen in epithelial cell membranes.
Specimen 3B: embryonic day 7.5; Mrpl3em1(IMPC)J/Mrpl3em1(IMPC)J (more )
Note: Double labeled: green - Cdh1; red - Pou5f1 (assay MGI:6445528).
Structure Level Pattern Image Note
TS8: conceptus Present 3B'' , 3B Expression is seen in epithelial cell membranes. Mutants appear to stall just prior to the onset of gastrulation.
Specimen 3C: embryonic day 7.5; Mrpl22tm1b(KOMP)Mbp/Mrpl22tm1b(KOMP)Mbp (more )
Note: Double labeled: green - Cdh1; red - Pou5f1 (assay MGI:6445528).
Structure Level Pattern Image Note
TS8: conceptus Present 3C , 3C'' Expression is seen in epithelial cell membranes. Mutants appear to stall just prior to the onset of gastrulation.
Specimen 3D: embryonic day 7.5; Mrpl44em1(IMPC)J/Mrpl44em1(IMPC)J (more )
Note: Double labeled: green - Cdh1; red - Pou5f1 (assay MGI:6445528).
Structure Level Pattern Image Note
TS8: conceptus Present 3D'' , 3D Expression is seen in epithelial cell membranes. Mutants appear to stall just prior to the onset of gastrulation.
Specimen 3E: embryonic day 7.5; Mrps18ctm1.1(KOMP)Vlcg/Mrps18ctm1.1(KOMP)Vlcg (more )
Note: Double labeled: green - Cdh1; red - Pou5f1 (assay MGI:6445528).
Structure Level Pattern Image Note
TS8: conceptus Present 3E'' , 3E Expression is seen in epithelial cell membranes. Mutants appear to stall just prior to the onset of gastrulation.
Specimen 3F: embryonic day 7.5; Mrps22tm1.1(KOMP)Vlcg/Mrps22tm1.1(KOMP)Vlcg (more )
Note: Double labeled: green - Cdh1; red - Pou5f1 (assay MGI:6445528).
Structure Level Pattern Image Note
TS8: conceptus Present 3F , 3F'' Expression is seen in epithelial cell membranes. Mutants appear to stall just prior to the onset of gastrulation.
Specimen 3G: embryonic day 5.5 (more )
Note: Early egg-cylinder stage embryo. Double labeled: green - Cdh1; red - Pou5f1 (assay MGI:6445528).
Structure Level Pattern Image Note
TS7: conceptus Present 3G'' , 3G Expression is seen in epithelial cell membranes.
Specimen 4A: embryonic day 7.5 (more )
Note: Littermate control; embryo is either +/+ or +/-. Double labeled: green - Cdh1; white - Trp53 (assay MGI:6445616).
Structure Level Pattern Image Note
TS11: conceptus Present 4A , 4A' Expression is seen in epithelial cell membranes.
Specimen 4B: embryonic day 7.5; Mrpl3em1(IMPC)J/Mrpl3em1(IMPC)J (more )
Note: Double labeled: green - Cdh1; white - Trp53 (assay MGI:6445616).
Structure Level Pattern Image Note
TS8: conceptus Present 4B , 4B' Expression is seen in epithelial cell membranes. Mutants appear to stall just prior to the onset of gastrulation.
Specimen 4C: embryonic day 7.5; Mrpl22tm1b(KOMP)Mbp/Mrpl22tm1b(KOMP)Mbp (more )
Note: Double labeled: green - Cdh1; white - Trp53 (assay MGI:6445616).
Structure Level Pattern Image Note
TS8: conceptus Present 4C , 4C' Expression is seen in epithelial cell membranes. Mutants appear to stall just prior to the onset of gastrulation.
Specimen 4D: embryonic day 7.5; Mrpl44em1(IMPC)J/Mrpl44em1(IMPC)J (more )
Note: Double labeled: green - Cdh1; white - Trp53 (assay MGI:6445616).
Structure Level Pattern Image Note
TS8: conceptus Present 4D , 4D' Expression is seen in epithelial cell membranes. Mutants appear to stall just prior to the onset of gastrulation.
Specimen 4E: embryonic day 7.5; Mrps18ctm1.1(KOMP)Vlcg/Mrps18ctm1.1(KOMP)Vlcg (more )
Note: Double labeled: green - Cdh1; white - Trp53 (assay MGI:6445616).
Structure Level Pattern Image Note
TS8: conceptus Present 4E , 4E' Expression is seen in epithelial cell membranes. Mutants appear to stall just prior to the onset of gastrulation.
Specimen 4F: embryonic day 7.5; Mrps22tm1.1(KOMP)Vlcg/Mrps22tm1.1(KOMP)Vlcg (more )
Note: Double labeled: green - Cdh1; white - Trp53 (assay MGI:6445616).
Structure Level Pattern Image Note
TS8: conceptus Present 4F' , 4F Expression is seen in epithelial cell membranes. Mutants appear to stall just prior to the onset of gastrulation.
Specimen 4G: embryonic day 5.5 (more )
Note: Early egg-cylinder stage embryo. Double labeled: green - Cdh1; white - Trp53 (assay MGI:6445616).
Structure Level Pattern Image Note
TS7: conceptus Present 4G , 4G' Expression is seen in epithelial cell membranes.
Specimen 4H: embryonic day 7.5 (more )
Note: Littermate control; embryo is either +/+ or +/-. Double labeled: green - Cdh1; white - Trp53 (assay MGI:6445616) and phosphorylated histone, a marker of dividing cells.
Structure Level Pattern Image Note
TS11: conceptus Present 4H' , 4H Expression is seen in epithelial cell membranes. Histone staining revealed the presence of cells in G2.
Specimen 4I: embryonic day 7.5; Mrpl3em1(IMPC)J/Mrpl3em1(IMPC)J (more )
Note: Double labeled: green - Cdh1; white - Trp53 (assay MGI:6445616) and phosphorylated histone, a marker of dividing cells.
Structure Level Pattern Image Note
TS8: conceptus Present 4I , 4I' Expression is seen in epithelial cell membranes. Mutants appear to stall just prior to the onset of gastrulation. Histone staining suggested there is an increase in cells arrested in G2 in the mutant.
Specimen 4J: embryonic day 7.5; Mrpl22tm1b(KOMP)Mbp/Mrpl22tm1b(KOMP)Mbp (more )
Note: Double labeled: green - Cdh1; white - Trp53 (assay MGI:6445616) and phosphorylated histone, a marker of dividing cells.
Structure Level Pattern Image Note
TS8: conceptus Present 4J' , 4J Expression is seen in epithelial cell membranes. Mutants appear to stall just prior to the onset of gastrulation. Histone staining suggested there is an increase in cells arrested in G2 in the mutant.
Specimen 4K: embryonic day 7.5; Mrpl44em1(IMPC)J/Mrpl44em1(IMPC)J (more )
Note: Double labeled: green - Cdh1; white - Trp53 (assay MGI:6445616) and phosphorylated histone, a marker of dividing cells.
Structure Level Pattern Image Note
TS8: conceptus Present 4K , 4K' Expression is seen in epithelial cell membranes. Mutants appear to stall just prior to the onset of gastrulation. Histone staining suggested there is an increase in cells arrested in G2 in the mutant.
Specimen 4L: embryonic day 7.5; Mrps18ctm1.1(KOMP)Vlcg/Mrps18ctm1.1(KOMP)Vlcg (more )
Note: Double labeled: green - Cdh1; white - Trp53 (assay MGI:6445616) and phosphorylated histone, a marker of dividing cells.
Structure Level Pattern Image Note
TS8: conceptus Present 4L , 4L' Expression is seen in epithelial cell membranes. Mutants appear to stall just prior to the onset of gastrulation. Histone staining suggested there is an increase in cells arrested in G2 in the mutant.
Specimen 4M: embryonic day 7.5; Mrps22tm1.1(KOMP)Vlcg/Mrps22tm1.1(KOMP)Vlcg (more )
Note: Double labeled: green - Cdh1; white - Trp53 (assay MGI:6445616) and phosphorylated histone, a marker of dividing cells.
Structure Level Pattern Image Note
TS8: conceptus Present 4M' , 4M Expression is seen in epithelial cell membranes. Mutants appear to stall just prior to the onset of gastrulation. Histone staining suggested there is an increase in cells arrested in G2 in the mutant.
Specimen 4N: embryonic day 5.5 (more )
Note: Early egg-cylinder stage embryo. Double labeled: green - Cdh1; white - Trp53 (assay MGI:6445616) and phosphorylated histone, a marker of dividing cells.
Structure Level Pattern Image Note
TS7: conceptus Present 4N , 4N' Expression is seen in epithelial cell membranes. Histone staining revealed the presence of cells in G2.
Specimen 4O: embryonic day 7.5 (more )
Note: Littermate control; embryo is either +/+ or +/-. Double labeled: green - Cdh1; white - 4-hydroxynonenal, used to reveal an increase in oxidative stress.
Structure Level Pattern Image Note
TS11: conceptus Present 4O , 4O' Expression is seen in epithelial cell membranes.
Specimen 4P: embryonic day 7.5; Mrpl3em1(IMPC)J/Mrpl3em1(IMPC)J (more )
Note: Double labeled: green - Cdh1; white - 4-hydroxynonenal, used to reveal an increase in oxidative stress.
Structure Level Pattern Image Note
TS8: conceptus Present 4P , 4P' Expression is seen in epithelial cell membranes. Mutants appear to stall just prior to the onset of gastrulation. Staining for 4HNE revealed no evidence of increased oxidative stress in the mutant.
Specimen 4Q: embryonic day 7.5; Mrpl22tm1b(KOMP)Mbp/Mrpl22tm1b(KOMP)Mbp (more )
Note: Double labeled: green - Cdh1; white - 4-hydroxynonenal, used to reveal an increase in oxidative stress.
Structure Level Pattern Image Note
TS8: conceptus Present 4Q , 4Q' Expression is seen in epithelial cell membranes. Mutants appear to stall just prior to the onset of gastrulation. Staining for 4HNE revealed no evidence of increased oxidative stress in the mutant.
Specimen 4R: embryonic day 7.5; Mrpl44em1(IMPC)J/Mrpl44em1(IMPC)J (more )
Note: Double labeled: green - Cdh1; white - 4-hydroxynonenal, used to reveal an increase in oxidative stress.
Structure Level Pattern Image Note
TS8: conceptus Present 4R , 4R' Expression is seen in epithelial cell membranes. Mutants appear to stall just prior to the onset of gastrulation. Staining for 4HNE revealed no evidence of increased oxidative stress in the mutant.
Specimen 4S: embryonic day 7.5; Mrps18ctm1.1(KOMP)Vlcg/Mrps18ctm1.1(KOMP)Vlcg (more )
Note: Double labeled: green - Cdh1; white - 4-hydroxynonenal, used to reveal an increase in oxidative stress.
Structure Level Pattern Image Note
TS8: epiblast Present 4S , 4S' Expression is seen in epithelial cell membranes. Mutants appear to stall just prior to the onset of gastrulation. Staining for 4HNE revealed no evidence of increased oxidative stress in the mutant.
Specimen 4T: embryonic day 7.5; Mrps22tm1.1(KOMP)Vlcg/Mrps22tm1.1(KOMP)Vlcg (more )
Note: Double labeled: green - Cdh1; white - 4-hydroxynonenal, used to reveal an increase in oxidative stress.
Structure Level Pattern Image Note
TS8: conceptus Present 4T , 4T' Expression is seen in epithelial cell membranes. Mutants appear to stall just prior to the onset of gastrulation. Staining for 4HNE revealed no evidence of increased oxidative stress in the mutant.
Specimen 4U: embryonic day 5.5 (more )
Note: Early egg-cylinder stage embryo. Double labeled: green - Cdh1; white - 4-hydroxynonenal, used to reveal an increase in oxidative stress.
Structure Level Pattern Image Note
TS7: conceptus Present 4U , 4U' Expression is seen in epithelial cell membranes.
Specimen 7A: embryonic day 7.5 (more )
Note: Littermate control; embryo is either +/+ or +/-. Double labeled: green - Cdh1; red - phosphorylated Cdc25c (assay MGI:6445619).
Structure Level Pattern Image Note
TS11: conceptus Present 7A , 7A' Expression is seen in epithelial cell membranes.
Specimen 7B: embryonic day 7.5; Mrpl3em1(IMPC)J/Mrpl3em1(IMPC)J (more )
Note: Double labeled: green - Cdh1; red - phosphorylated Cdc25c (assay MGI:6445619).
Structure Level Pattern Image Note
TS8: conceptus Present 7B , 7B' Expression is seen in epithelial cell membranes. Mutants appear to stall just prior to the onset of gastrulation.
Specimen 7C: embryonic day 5.5 (more )
Note: Early egg-cylinder stage embryo. Double labeled: green - Cdh1; red - phosphorylated Cdc25c (assay MGI:6445619).
Structure Level Pattern Image Note
TS7: conceptus Present 7C' , 7C Expression is seen in epithelial cell membranes.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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