About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:138715 Li WY, et al., Signaling through Tgf-beta type I receptor Alk5 is required for upper lip fusion. Mech Dev. 2008 Sep-Oct;125(9-10):874-82
Assay type: RNA in situ
MGI Accession ID: MGI:6441970
Gene symbol: Shh
Gene name: sonic hedgehog
Probe: Shh cDNA3
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3A: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: 1st branchial arch mandibular component ectoderm Present 3A
TS16: 1st branchial arch maxillary component ectoderm Present 3A
Specimen 3B: embryonic day 10.0; Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl, Tg(Nes-cre)1Atp/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS16: 1st branchial arch mandibular component ectoderm Weak Regionally restricted 3B Diminished expression levels over maxillary and mandibular processes compared to controls.
TS16: 1st branchial arch maxillary component ectoderm Weak Regionally restricted 3B Diminished expression levels over maxillary and mandibular processes compared to controls.
Specimen 3C: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: 1st branchial arch mandibular component ectoderm Present 3C
TS16: 1st branchial arch maxillary component ectoderm Present 3C
Specimen 3D: embryonic day 10.0; Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl, Tg(Nes-cre)1Atp/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS16: 1st branchial arch mandibular component ectoderm Weak Regionally restricted 3D Diminished expression levels over maxillary and mandibular processes compared to controls.
TS16: 1st branchial arch maxillary component ectoderm Weak Regionally restricted 3D Diminished expression levels over maxillary and mandibular processes compared to controls.
Specimen 3E: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: 1st branchial arch maxillary component Present 3E
Specimen 3F: embryonic day 11.0; Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl, Tg(Nes-cre)1Atp/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS18: 1st branchial arch maxillary component Present Regionally restricted 3F Difference at E11 was more slight and most likely a reflection of hypoplastic maxillary process in mutant.
Specimen 3G: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: 1st branchial arch maxillary component Present 3G
Specimen 3H: embryonic day 11.0; Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl, Tg(Nes-cre)1Atp/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS18: 1st branchial arch maxillary component Present 3H
Specimen 3I: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: latero-nasal process Ambiguous 3I
Specimen 3J: embryonic day 12.0; Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl, Tg(Nes-cre)1Atp/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: latero-nasal process Strong Punctate 3J Punctate area of intense expression on distal tip of unfused lateral nasal process.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory