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Gene Expression Data
Assay Details
Assay
Reference: J:80177 Aoto K, et al., Mouse GLI3 Regulates Fgf8 Expression and Apoptosis in the Developing Neural Tube, Face, and Limb Bud. Dev Biol. 2002 Nov 15;251(2):320-32
Assay type: RNA in situ
MGI Accession ID: MGI:5502216
Gene symbol: Pax6
Gene name: paired box 6
Probe: Pax6 probe
Probe preparation: labelled with digoxigenin
Results
Specimen 1F: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: telencephalon Present Regionally restricted 1F Expression was detected in the dorsal telencephalon.
TS19: diencephalon Present Regionally restricted 1F Expression was detected in the dorsal diencephalon (prosomeres P1-P3).
TS19: eye Present Regionally restricted 1F Expression was detected in the optic cup.
Specimen 1G: embryonic day 11.5; Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS19: telencephalon Present Regionally restricted 1G Expression was greatly reduced. Expression in dorsal telencephalon was shifted toward the dorsal side.
TS19: diencephalon Present Regionally restricted 1G Expression in prosomere 3 of the diencephalon was expanded. There was no change to expression in prosomeres 1 and 2.
Specimen 2Q: embryonic day 10.5 (more )
Note: Also stained for En2 (assay MGI:5502317).
Structure Level Pattern Image Note
TS17: diencephalon Present 2Q Expression in diencephalon (defined by double-headed red arrow in figure pane).
Specimen 2R: embryonic day 10.5; Gli3Xt-J/Gli3Xt-J (more )
Note: Also stained for En2 (assay MGI:5502317).
Structure Level Pattern Image Note
TS17: diencephalon Present 2R Expression in diencephalon (defined by double-headed red arrow in figure pane). There was a significant increase in the size of the P3 region of the diencephalon.
Specimen 3C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: optic cup Present 3C
Specimen 3D: embryonic day 10.5; Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS17: optic cup Weak 3D
Specimen 6P: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: telencephalon Present Regionally restricted 6P Expression was detected in the dorsal telencephalon.
TS17: diencephalon Present 6P
Specimen 6Q: embryonic day 10.5; Shhtm1Amc/Shhtm1Amc (more )
Structure Level Pattern Image Note
TS17: telencephalon Present Regionally restricted 6Q Expression was shifted more ventrally.
Specimen 6R: embryonic day 10.5; Gli3Xt-J/Gli3+, Shhtm1Amc/Shhtm1Amc (more )
Structure Level Pattern Image Note
TS17: telencephalon Present Regionally restricted 6R Expression was shifted more ventrally.
Specimen 6S: embryonic day 10.5; Gli3Xt-J/Gli3Xt-J, Shhtm1Amc/Shhtm1Amc (more )
Structure Level Pattern Image Note
TS17: telencephalon Present 6S
Specimen 6T: embryonic day 10.5; Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS17: telencephalon Present 6T
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory