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Pax6 probe Probe Detail
Nucleotide
Probe/Clone
  • Name
    Pax6 probe
  • Sequence Type
    cDNA
  • ID
    MGI:1277653
  • Region Covered
    includes a 3' portion of the paired box
  • Child Clone
  • Vector Type
    Plasmid
  • Insert Site
    EcoRI/NheI
Source
  • Species
    mouse, laboratory
Genes
Pax6 paired box 6
Expression
  • Assay Results
    443
References
J:1914 Walther C, et al., Pax-6, a murine paired box gene, is expressed in the developing CNS. Development. 1991 Dec;113(4):1435-49
J:17132 Stoykova A, et al., Roles of Pax-genes in developing and adult brain as suggested by expression patterns. J Neurosci. 1994 Mar;14(3 Pt 2):1395-412
J:18916 Dickinson ME, et al., Evidence for a mitogenic effect of Wnt-1 in the developing mammalian central nervous system. Development. 1994 Jun;120(6):1453-71
J:19895 Ang SL, et al., HNF-3 beta is essential for node and notochord formation in mouse development. Cell. 1994 Aug 26;78(4):561-74
J:21617 Gunther T, et al., Open brain, a new mouse mutant with severe neural tube defects, shows altered gene expression patterns in the developing spinal cord. Development. 1994 Nov;120(11):3119-30
J:30342 Oliver G, et al., Six3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development. Development. 1995 Dec;121(12):4045-55
J:34768 Tremblay P, et al., Inhibition of floor plate differentiation by Pax3: evidence from ectopic expression in transgenic mice. Development. 1996 Aug;122(8):2555-67
J:36832 Stoykova A, et al., Forebrain patterning defects in Small eye mutant mice. Development. 1996 Nov;122(11):3453-65
J:39280 Furukawa T, et al., rax, a novel paired-type homeobox gene, shows expression in the anterior neural fold and developing retina. Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):3088-93
J:41030 Mastick GS, et al., Pax-6 functions in boundary formation and axon guidance in the embryonic mouse forebrain. Development. 1997 May;124(10):1985-97
J:41809 Filosa S, et al., goosecoid and HNF-3 beta genetically interact to regulate neural tube patterning during mouse embryogenesis. Development. 1997 JUL;124(14):2843-2854
J:43761 Stoykova A, et al., Pax6-dependent regulation of adhesive patterning, R-cadherin expression and boundary formation in developing forebrain. Development. 1997 Oct;124(19):3765-77
J:45681 Suda Y, et al., Cooperation between Otx1 and Otx2 genes in developmental patterning of rostral brain. Mech Dev. 1997 Dec;69(1-2):125-41
J:49164 Ding Q, et al., Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice. Development. 1998 Jul;125(14):2533-43
J:51693 Grimm C, et al., Aphakia (ak), a mouse mutation affecting early eye development: fine mapping, consideration of candidate genes and altered Pax6 and Six3 gene expression pattern. Dev Genet. 1998;23(4):299-316
J:52338 Bassett JH, et al., Studies of the murine homolog of the multiple endocrine neoplasia type 1 (MEN1) gene, men1. J Bone Miner Res. 1999 Jan;14(1):3-10
J:53903 Theil T, et al., Gli3 is required for Emx gene expression during dorsal telencephalon development. Development. 1999 Aug;126(16):3561-71
J:55154 Schwarz M, et al., Pax2/5 and Pax6 subdivide the early neural tube into three domains. Mech Dev. 1999 Apr;82(1-2):29-39
J:59472 Dou CL, et al., Dual role of brain factor-1 in regulating growth and patterning of the cerebral hemispheres. Cereb Cortex. 1999 Sep;9(6):543-50
J:56583 Ring BZ, et al., Regulation of mouse lens fiber cell development and differentiation by the Maf gene. Development. 2000 Jan;127(2):307-17
J:60773 Lu QR, et al., Sonic hedgehog--regulated oligodendrocyte lineage genes encoding bHLH proteins in the mammalian central nervous system. Neuron. 2000 Feb;25(2):317-29
J:64590 Schwarz M, et al., Spatial specification of mammalian eye territories by reciprocal transcriptional repression of pax2 and pax6. Development. 2000 Oct;127(20):4325-34
J:65298 Corbin JG, et al., The gsh2 homeodomain gene controls multiple aspects of telencephalic development. Development. 2000 Dec;127(23):5007-20
J:70745 Suda Y, et al., Emx2 directs the development of diencephalon in cooperation with Otx2. Development. 2001 Jul;128(13):2433-50
J:71951 Ohnemus S, et al., Different levels of Hoxa2 are required for particular developmental processes. Mech Dev. 2001 Oct;108(1-2):135-47
J:74631 Tian E, et al., Otx2 is required to respond to signals from anterior neural ridge for forebrain specification. Dev Biol. 2002 Feb 15;242(2):204-23
J:80177 Aoto K, et al., Mouse GLI3 Regulates Fgf8 Expression and Apoptosis in the Developing Neural Tube, Face, and Limb Bud. Dev Biol. 2002 Nov 15;251(2):320-32
J:86839 Liguori GL, et al., Anterior neural plate regionalization in cripto null mutant mouse embryos in the absence of node and primitive streak. Dev Biol. 2003 Dec 15;264(2):537-49
J:90405 Shinozaki K, et al., Emx1 and Emx2 cooperate in initial phase of archipallium development. Mech Dev. 2004 May;121(5):475-89
J:91011 Kurokawa D, et al., Regulation of Otx2 expression and its functions in mouse forebrain and midbrain. Development. 2004 Jul;131(14):3319-31
J:91012 Kurokawa D, et al., Regulation of Otx2 expression and its functions in mouse epiblast and anterior neuroectoderm. Development. 2004 Jul;131(14):3307-17
J:97076 Furushima K, et al., Characterization of Opr deficiency in mouse brain: Subtle defects in dorsomedial telencephalon and medioventral forebrain. Dev Dyn. 2005 Apr;232(4):1056-61
J:99098 Hester M, et al., Smad1 and Smad8 function similarly in mammalian central nervous system development. Mol Cell Biol. 2005 Jun;25(11):4683-92
J:109515 Paracchini S, et al., The chromosome 6p22 haplotype associated with dyslexia reduces the expression of KIAA0319, a novel gene involved in neuronal migration. Hum Mol Genet. 2006 May 15;15(10):1659-66
J:122557 Furushima K, et al., Mouse homologues of Shisa antagonistic to Wnt and Fgf signalings. Dev Biol. 2007 Jun 15;306(2):480-92
J:134435 Anselme I, et al., Defects in brain patterning and head morphogenesis in the mouse mutant Fused toes. Dev Biol. 2007 Apr 1;304(1):208-20
J:142648 Castranio T, et al., Bmp2 is required for cephalic neural tube closure in the mouse. Dev Dyn. 2008 Dec 18;238(1):110-122

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory