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Gene Expression Data
Assay Details
Assay
Reference: J:95017 Parlato R, et al., An integrated regulatory network controlling survival and migration in thyroid organogenesis. Dev Biol. 2004 Dec 15;276(2):464-75
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5495807
Gene symbol: Nkx2-1
Gene name: NK2 homeobox 1
Antibody: anti-Nkx2.1
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 1A: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: thyroid primordium Present 1A

Specimen 1B: embryonic day 9.0; Hhextm1Rbe/Hhextm1Rbe (more )
Structure Level Pattern Image Note
TS14: thyroid primordium Present 1B Expression is comparable to the wild type.

Specimen 1C: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: thyroid primordium Present 1C

Specimen 1D: embryonic day 10.0; Hhextm1Rbe/Hhextm1Rbe (more )
Structure Level Pattern Image Note
TS16: thyroid primordium Present 1D Expression is not significantly reduced.

Specimen 3A: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: thyroid primordium Present 3A

Specimen 3B: embryonic day 9.0; Pax8tm1Pgr/Pax8tm1Pgr (more )
Structure Level Pattern Image Note
TS14: thyroid primordium Present 3B Expression is comparable to those of the wild-type.

Specimen 3C: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: thyroid primordium Present 3C

Specimen 3D: embryonic day 10.0; Pax8tm1Pgr/Pax8tm1Pgr (more )
Structure Level Pattern Image Note
TS16: thyroid primordium Present 3D

Specimen 5A: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: thyroid gland Present 5A

Specimen 5B: embryonic day 11.0; Pax8tm1Pgr/Pax8tm1Pgr (more )
Structure Level Pattern Image Note
TS18: thyroid gland Present 5B

Specimen 6C: embryonic day 10.5; Foxe1tm1Rdl/Foxe1tm1Rdl (more )
Structure Level Pattern Image Note
TS17: thyroid primordium Present 6C

Specimen 6D: embryonic day 10.5; Foxe1tm1Rdl/Foxe1tm1Rdl, Nkx2-1tm1Rdl/Nkx2-1+ (more )
Structure Level Pattern Image Note
TS17: thyroid primordium Present 6D

Specimen 6E: embryonic day 10.5; Foxe1tm1Rdl/Foxe1tm1Rdl, Nkx2-1tm1Shk/Nkx2-1+ (more )
Structure Level Pattern Image Note
TS17: thyroid primordium Present 6E

Specimen 7E: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: thyroid primordium Present 7E

Specimen 7H: embryonic day 10.0; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS16: thyroid primordium Present 7H Expression is comparable to the wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory