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Foxe1tm1Rdl
Targeted Allele Detail
Summary
Symbol: Foxe1tm1Rdl
Name: forkhead box E1; targeted mutation 1, Roberto Di Lauro
MGI ID: MGI:2181780
Synonyms: Titf2-
Gene: Foxe1  Location: Chr4:46343644-46345774 bp, + strand  Genetic Position: Chr4, 24.68 cM
Alliance: Foxe1tm1Rdl page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:48970
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    A neomycin selection cassette was inserted 180 base pairs upstream of the translational start codon. (J:48970)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 21 assay results
In Structures Affected by this Mutation: 6 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Foxe1 Mutation:  9 strains or lines available
References
Original:  J:48970 De Felice M, et al., A mouse model for hereditary thyroid dysgenesis and cleft palate. Nat Genet. 1998 Aug;19(4):395-8
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory