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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Jarid2em1Chend
endonuclease-mediated mutation 1, Chen Davidovich
MGI:8326310
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Jarid2em1Chend/Jarid2em1Chend Not Specified MGI:8326761
cx2
 		Jarid2em1Chend/Jarid2+
Lcorem1Chend/Lcorem1Chend 		involves: C57BL/6J MGI:8326762
cx3
 		Jarid2em1Chend/Jarid2em1Chend
Lcorem1Chend/Lcor+ 		involves: C57BL/6J MGI:8326763


Genotype
MGI:8326761
hm1
Allelic
Composition		 Jarid2em1Chend/Jarid2em1Chend
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Jarid2em1Chend mutation (0 available); any Jarid2 mutation (374 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, complete penetrance ( J:383110 )
• no homozygous mice born

skeleton
lumbar vertebral transformation ( J:383110 )
• L1 transformed into a thoracic vertebra with rib(s) in E12.5 and E14.5 embryos




Genotype
MGI:8326762
cx2
Allelic
Composition		 Jarid2em1Chend/Jarid2+
Lcorem1Chend/Lcorem1Chend
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Jarid2em1Chend mutation (0 available); any Jarid2 mutation (374 available)
Lcorem1Chend mutation (0 available); any Lcor mutation (20 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
skeleton
lumbar vertebral transformation ( J:383110 )
• L1 transformed into a thoracic vertebra with rib(s) in E12.5 and E14.5 embryos




Genotype
MGI:8326763
cx3
Allelic
Composition		 Jarid2em1Chend/Jarid2em1Chend
Lcorem1Chend/Lcor+
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Jarid2em1Chend mutation (0 available); any Jarid2 mutation (374 available)
Lcorem1Chend mutation (0 available); any Lcor mutation (20 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
skeleton
lumbar vertebral transformation ( J:383110 )
• L1 transformed into a thoracic vertebra with rib(s) in E12.5 and E14.5 embryos




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/05/2026
MGI 6.24 		The Jackson Laboratory