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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tmx3em1Jlp
endonuclease-mediated mutation 1, Jose de la Pompa
MGI:7543636
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Bcl7aem1Jlp/Bcl7a+
Cep192em1Jlp/Cep192+
Mib1em2Jlp/Mib1+
Tmx3em1Jlp/Tmx3+ 		C57BL/6-Bcl7aem1Jlp Cep192em1Jlp Mib1em2Jlp Tmx3em1Jlp MGI:7544923
cx2
 		Cep192em1Jlp/Cep192+
Mib1em2Jlp/Mib1+
Tmx3em1Jlp/Tmx3+ 		C57BL/6-Cep192em1Jlp Mib1em2Jlp Tmx3em1Jlp MGI:7544921


Genotype
MGI:7544923
cx1
Allelic
Composition		 Bcl7aem1Jlp/Bcl7a+
Cep192em1Jlp/Cep192+
Mib1em2Jlp/Mib1+
Tmx3em1Jlp/Tmx3+
Genetic
Background		 C57BL/6-Bcl7aem1Jlp Cep192em1Jlp Mib1em2Jlp Tmx3em1Jlp
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bcl7aem1Jlp mutation (0 available); any Bcl7a mutation (29 available)
Cep192em1Jlp mutation (0 available); any Cep192 mutation (75 available)
Mib1em2Jlp mutation (0 available); any Mib1 mutation (55 available)
Tmx3em1Jlp mutation (0 available); any Tmx3 mutation (26 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
bicuspid aortic valve ( J:338889 )
• in E16.5 embryos




Genotype
MGI:7544921
cx2
Allelic
Composition		 Cep192em1Jlp/Cep192+
Mib1em2Jlp/Mib1+
Tmx3em1Jlp/Tmx3+
Genetic
Background		 C57BL/6-Cep192em1Jlp Mib1em2Jlp Tmx3em1Jlp
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cep192em1Jlp mutation (0 available); any Cep192 mutation (75 available)
Mib1em2Jlp mutation (0 available); any Mib1 mutation (55 available)
Tmx3em1Jlp mutation (0 available); any Tmx3 mutation (26 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
bicuspid aortic valve ( J:338889 )
• in E16.5 embryos




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory