Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbxw7tm1Iken mutation
(0 available);
any
Fbxw7 mutation
(82 available)
Krastm4Tyj mutation
(9 available);
any
Kras mutation
(76 available)
Speer6-ps1Tg(Alb-cre)21Mgn mutation
(6 available);
any
Speer6-ps1 mutation
(4 available)
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endocrine/exocrine glands
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• bile duct hyperplasia is seen in some mice at 8 months of age
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• bile duct dilation is seen in some mice at 8 months of age
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liver/biliary system
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• bile duct hyperplasia is seen in some mice at 8 months of age
|
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• bile duct dilation is seen in some mice at 8 months of age
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbxw7tm1Iken mutation
(0 available);
any
Fbxw7 mutation
(82 available)
Krastm4Tyj mutation
(9 available);
any
Kras mutation
(76 available)
Speer6-ps1Tg(Alb-cre)21Mgn mutation
(6 available);
any
Speer6-ps1 mutation
(4 available)
|
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liver/biliary system
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• all mice develop cholangiocarcinoma-like lesions composed of dysplastic dust-like structures surrounded by fibrosis within 2 months of birth
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neoplasm
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• all mice develop cholangiocarcinoma-like lesions composed of dysplastic dust-like structures surrounded by fibrosis within 2 months of birth
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbxw7tm1Iken mutation
(0 available);
any
Fbxw7 mutation
(82 available)
Speer6-ps1Tg(Alb-cre)21Mgn mutation
(6 available);
any
Speer6-ps1 mutation
(4 available)
|
|
|
endocrine/exocrine glands
|
• hyperplasia of bile ducts throughout the liver at 12 months of age
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• dilatation of bile ducts throughout the liver at 12 months of age
|
liver/biliary system
|
• hyperplasia of bile ducts throughout the liver at 12 months of age
|
|
• dilatation of bile ducts throughout the liver at 12 months of age
|