Phenotypes associated with this allele

• Allele Symbol: Tent5a^{em1(IMPC)Ccpcz}
• Allele Name: endonuclease-mediated mutation 1, Institute of Molecular Genetics
• Allele ID: MGI:6152705
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tent5a^em1(IMPC)Ccpcz/Tent5a^em1(IMPC)Ccpcz	C57BL/6N-Tent5a^em1(IMPC)Ccpcz/Ccpcz	MGI:6408708

Genotype
MGI:6408708

hm1

• Allelic Composition: Tent5a^{em1(IMPC)Ccpcz}/Tent5a^{em1(IMPC)Ccpcz}
• Genetic Background: C57BL/6N-Tent5a^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Tent5a

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

enhanced cued conditioning behavior ( J:211773 )

♂

IMPC - CCP-IMG

decreased exploration in new environment ( J:211773 )

IMPC - CCP-IMG

increased anxiety-related response ( J:211773 )

IMPC - CCP-IMG

increased freezing behavior ( J:211773 )

♀

IMPC - CCP-IMG

impaired righting response ( J:211773 )

♂

IMPC - CCP-IMG

abnormal gait ( J:211773 )

♂

IMPC - CCP-IMG

decreased locomotor activity ( J:211773 )

IMPC - CCP-IMG

craniofacial

abnormal cranium morphology ( J:211773 )

IMPC - CCP-IMG

abnormal tooth morphology ( J:211773 )

IMPC - CCP-IMG

abnormal mandible morphology ( J:211773 )

♂

IMPC - CCP-IMG

growth/size/body

abnormal tooth morphology ( J:211773 )

IMPC - CCP-IMG

abnormal mandible morphology ( J:211773 )

♂

IMPC - CCP-IMG

decreased body weight ( J:211773 )

IMPC - CCP-IMG

hematopoietic system

thrombocytosis ( J:211773 )

IMPC - CCP-IMG

decreased lymphocyte cell number ( J:211773 )

♀

IMPC - CCP-IMG

decreased Ly6C-positive mature NK cell number ( J:211773 )

IMPC - CCP-IMG

increased leukocyte cell number ( J:211773 )

♀

IMPC - CCP-IMG

increased granulocyte number ( J:211773 )

♀

IMPC - CCP-IMG

increased neutrophil cell number ( J:211773 )

♀

IMPC - CCP-IMG

increased monocyte cell number ( J:211773 )

♀

IMPC - CCP-IMG

homeostasis/metabolism

decreased circulating glucose level ( J:211773 )

IMPC - CCP-IMG

increased circulating potassium level ( J:211773 )

♂

IMPC - CCP-IMG

increased circulating alkaline phosphatase level ( J:211773 )

IMPC - CCP-IMG

decreased circulating serum albumin level ( J:211773 )

♀

IMPC - CCP-IMG

decreased respiratory quotient ( J:211773 )

♂

IMPC - CCP-IMG

immune system

decreased lymphocyte cell number ( J:211773 )

♀

IMPC - CCP-IMG

decreased Ly6C-positive mature NK cell number ( J:211773 )

IMPC - CCP-IMG

increased leukocyte cell number ( J:211773 )

♀

IMPC - CCP-IMG

increased granulocyte number ( J:211773 )

♀

IMPC - CCP-IMG

increased neutrophil cell number ( J:211773 )

♀

IMPC - CCP-IMG

increased monocyte cell number ( J:211773 )

♀

IMPC - CCP-IMG

limbs/digits/tail

abnormal humerus morphology ( J:211773 )

IMPC - CCP-IMG

abnormal radius morphology ( J:211773 )

IMPC - CCP-IMG

abnormal ulna morphology ( J:211773 )

IMPC - CCP-IMG

abnormal femur morphology ( J:211773 )

♂

IMPC - CCP-IMG

abnormal fibula morphology ( J:211773 )

♂

IMPC - CCP-IMG

abnormal tibia morphology ( J:211773 )

♂

IMPC - CCP-IMG

short tibia ( J:211773 )

♀

IMPC - CCP-IMG

nervous system

decreased prepulse inhibition ( J:211773 )

IMPC - CCP-IMG

skeleton

abnormal cranium morphology ( J:211773 )

IMPC - CCP-IMG

abnormal tooth morphology ( J:211773 )

IMPC - CCP-IMG

abnormal mandible morphology ( J:211773 )

♂

IMPC - CCP-IMG

abnormal humerus morphology ( J:211773 )

IMPC - CCP-IMG

abnormal radius morphology ( J:211773 )

IMPC - CCP-IMG

abnormal ulna morphology ( J:211773 )

IMPC - CCP-IMG

abnormal femur morphology ( J:211773 )

♂

IMPC - CCP-IMG

abnormal fibula morphology ( J:211773 )

♂

IMPC - CCP-IMG

abnormal tibia morphology ( J:211773 )

♂

IMPC - CCP-IMG

short tibia ( J:211773 )

♀

IMPC - CCP-IMG

abnormal scapula morphology ( J:211773 )

IMPC - CCP-IMG

abnormal pelvic girdle bone morphology ( J:211773 )

IMPC - CCP-IMG

abnormal rib morphology ( J:211773 )

IMPC - CCP-IMG

abnormal spine curvature ( J:211773 )

IMPC - CCP-IMG

scoliosis ( J:211773 )

♀

IMPC - CCP-IMG

abnormal bone structure ( J:211773 )

IMPC - CCP-IMG

abnormal joint morphology ( J:211773 )

IMPC - CCP-IMG