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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Slc12a2tm1.1Jheb
targeted mutation 1.1, Jean M Hebert
MGI:5538339
Summary 6 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Slc12a2tm1.1Jheb/Slc12a2tm1.1Jheb
Foxg1tm1(cre)Skm/Foxg1+ 		involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:5538347
cn2
 		Slc12a2tm1.1Jheb/Slc12a2tm1.1Jheb
Emx1tm1(cre)Krj/Emx1+ 		involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6 MGI:5538342
cn3
 		Slc12a2tm1.1Jheb/Slc12a2tm1.1Jheb
En1tm2(cre)Wrst/En1+ 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:5538345
cn4
 		Slc12a2tm1.1Jheb/Slc12a2tm1.1Jheb
Tbx1tm6(cre)Bld/Tbx1+
Tg(Pax2-cre)1Akg/0 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:5538349
cn5
 		Slc12a2tm1.1Jheb/Slc12a2tm1.1Jheb
Tg(mI56i-cre,EGFP)1Kc/0 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N MGI:5538344
cn6
 		Slc12a2tm1.1Jheb/Slc12a2tm1.1Jheb
Tg(Nes-cre)1Atp/0 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N MGI:5538346


Genotype
MGI:5538347
cn1
Allelic
Composition		 Slc12a2tm1.1Jheb/Slc12a2tm1.1Jheb
Foxg1tm1(cre)Skm/Foxg1+
Genetic
Background		 involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxg1tm1(cre)Skm mutation (2 available); any Foxg1 mutation (28 available)
Slc12a2tm1.1Jheb mutation (0 available); any Slc12a2 mutation (58 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological

hearing/vestibular/ear
abnormal inner ear morphology ( J:201156 )
• collapse of the membranes of the vestibular compartments
abnormal crista ampullaris morphology ( J:201156 )
• cristae degeneration




Genotype
MGI:5538342
cn2
Allelic
Composition		 Slc12a2tm1.1Jheb/Slc12a2tm1.1Jheb
Emx1tm1(cre)Krj/Emx1+
Genetic
Background		 involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Emx1tm1(cre)Krj mutation (2 available); any Emx1 mutation (34 available)
Slc12a2tm1.1Jheb mutation (0 available); any Slc12a2 mutation (58 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
behavior/neurological phenotype ( J:201156 )
N
• no behavioral abnormalities are detected




Genotype
MGI:5538345
cn3
Allelic
Composition		 Slc12a2tm1.1Jheb/Slc12a2tm1.1Jheb
En1tm2(cre)Wrst/En1+
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
En1tm2(cre)Wrst mutation (1 available); any En1 mutation (32 available)
Slc12a2tm1.1Jheb mutation (0 available); any Slc12a2 mutation (58 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
behavior/neurological phenotype ( J:201156 )
N
• no behavioral abnormalities are detected




Genotype
MGI:5538349
cn4
Allelic
Composition		 Slc12a2tm1.1Jheb/Slc12a2tm1.1Jheb
Tbx1tm6(cre)Bld/Tbx1+
Tg(Pax2-cre)1Akg/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc12a2tm1.1Jheb mutation (0 available); any Slc12a2 mutation (58 available)
Tbx1tm6(cre)Bld mutation (1 available); any Tbx1 mutation (34 available)
Tg(Pax2-cre)1Akg mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological

hearing/vestibular/ear
abnormal inner ear morphology ( J:201156 )
• collapse of the membranes of the vestibular compartments
abnormal crista ampullaris morphology ( J:201156 )
• cristae degeneration




Genotype
MGI:5538344
cn5
Allelic
Composition		 Slc12a2tm1.1Jheb/Slc12a2tm1.1Jheb
Tg(mI56i-cre,EGFP)1Kc/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc12a2tm1.1Jheb mutation (0 available); any Slc12a2 mutation (58 available)
Tg(mI56i-cre,EGFP)1Kc mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
behavior/neurological phenotype ( J:201156 )
N
• no behavioral abnormalities are detected




Genotype
MGI:5538346
cn6
Allelic
Composition		 Slc12a2tm1.1Jheb/Slc12a2tm1.1Jheb
Tg(Nes-cre)1Atp/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc12a2tm1.1Jheb mutation (0 available); any Slc12a2 mutation (58 available)
Tg(Nes-cre)1Atp mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
behavior/neurological phenotype ( J:201156 )
N
• no behavioral abnormalities are detected




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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory