All Phenotypes Slc12a2<tm1.1Jheb> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Slc12a2^tm1.1Jheb
targeted mutation 1.1, Jean M Hebert
MGI:5538339

Summary

6 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Slc12a2^tm1.1Jheb/Slc12a2^tm1.1Jheb Foxg1^tm1(cre)Skm/Foxg1⁺	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6	MGI:5538347
cn2	Slc12a2^tm1.1Jheb/Slc12a2^tm1.1Jheb Emx1^tm1(cre)Krj/Emx1⁺	involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6	MGI:5538342
cn3	Slc12a2^tm1.1Jheb/Slc12a2^tm1.1Jheb En1^tm2(cre)Wrst/En1⁺	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	MGI:5538345
cn4	Slc12a2^tm1.1Jheb/Slc12a2^tm1.1Jheb Tbx1^tm6(cre)Bld/Tbx1⁺ Tg(Pax2-cre)1Akg/0	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	MGI:5538349
cn5	Slc12a2^tm1.1Jheb/Slc12a2^tm1.1Jheb Tg(mI56i-cre,-EGFP)1Kc/0	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N	MGI:5538344
cn6	Slc12a2^tm1.1Jheb/Slc12a2^tm1.1Jheb Tg(Nes-cre)1Atp/0	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N	MGI:5538346

Allelic Composition	Slc12a2^tm1.1Jheb/Slc12a2^tm1.1Jheb Foxg1^tm1(cre)Skm/Foxg1⁺
Genetic Background	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxg1^tm1(cre)Skm mutation (2 available); any Foxg1 mutation (31 available)
Slc12a2^tm1.1Jheb mutation (0 available); any Slc12a2 mutation (59 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

hyperactivity ( J:201156 )

circling ( J:201156 )

hearing/vestibular/ear

abnormal inner ear morphology ( J:201156 )

• collapse of the membranes of the vestibular compartments

collapsed Reissner membrane ( J:201156 )

abnormal crista ampullaris morphology ( J:201156 )

• cristae degeneration

utricular degeneration ( J:201156 )

vestibular saccular degeneration ( J:201156 )

Allelic Composition	Slc12a2^tm1.1Jheb/Slc12a2^tm1.1Jheb Emx1^tm1(cre)Krj/Emx1⁺
Genetic Background	involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Emx1^tm1(cre)Krj mutation (2 available); any Emx1 mutation (30 available)
Slc12a2^tm1.1Jheb mutation (0 available); any Slc12a2 mutation (59 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:201156 )

N	• no behavioral abnormalities are detected

Allelic Composition	Slc12a2^tm1.1Jheb/Slc12a2^tm1.1Jheb En1^tm2(cre)Wrst/En1⁺
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
En1^tm2(cre)Wrst mutation (1 available); any En1 mutation (34 available)
Slc12a2^tm1.1Jheb mutation (0 available); any Slc12a2 mutation (59 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:201156 )

N	• no behavioral abnormalities are detected

Allelic Composition	Slc12a2^tm1.1Jheb/Slc12a2^tm1.1Jheb Tbx1^tm6(cre)Bld/Tbx1⁺ Tg(Pax2-cre)1Akg/0
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc12a2^tm1.1Jheb mutation (0 available); any Slc12a2 mutation (59 available)
Tbx1^tm6(cre)Bld mutation (1 available); any Tbx1 mutation (36 available)
Tg(Pax2-cre)1Akg mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

hyperactivity ( J:201156 )

circling ( J:201156 )

hearing/vestibular/ear

abnormal inner ear morphology ( J:201156 )

• collapse of the membranes of the vestibular compartments

collapsed Reissner membrane ( J:201156 )

abnormal crista ampullaris morphology ( J:201156 )

• cristae degeneration

utricular degeneration ( J:201156 )

vestibular saccular degeneration ( J:201156 )

Allelic Composition	Slc12a2^tm1.1Jheb/Slc12a2^tm1.1Jheb Tg(mI56i-cre,-EGFP)1Kc/0
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc12a2^tm1.1Jheb mutation (0 available); any Slc12a2 mutation (59 available)
Tg(mI56i-cre,-EGFP)1Kc mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:201156 )

N	• no behavioral abnormalities are detected

Allelic Composition	Slc12a2^tm1.1Jheb/Slc12a2^tm1.1Jheb Tg(Nes-cre)1Atp/0
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc12a2^tm1.1Jheb mutation (0 available); any Slc12a2 mutation (59 available)
Tg(Nes-cre)1Atp mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:201156 )

N	• no behavioral abnormalities are detected

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