Analysis Tools|
Allele Symbol Allele Name Allele ID |
Tet1tm1Gxu targeted mutation 1, Guo-Liang Xu MGI:5523868 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• adult neural progenitor cells transfected with a cre-expressing adenovirus exhibit reduced neurosphere growth in culture compared with control cells
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• adult neural progenitor cells transfected with a cre-expressing adenovirus exhibit reduced neurosphere growth in culture compared with control cells
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• mice treated with tamoxifen at 2 months of age exhibit impaired adult neurogenesis compared with control mice
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• mice treated with tamoxifen at 2 months of age exhibit decreased proliferation of intermediate progenitor cells in the dentate gyrus compared with control mice
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• mice treated with tamoxifen at 2 months of age exhibit impaired adult neurogenesis compared with control mice
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• mice treated with tamoxifen at 2 months of age exhibit decreased proliferation of intermediate progenitor cells in the dentate gyrus compared with control mice
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/30/2025 MGI 6.24 |
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