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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Med23tm1Gwan
targeted mutation 1, Gang Wang
MGI:5441008
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Med23tm1Gwan/Med23tm1Gwan involves: 129 * C57BL/6 MGI:5441009


Genotype
MGI:5441009
cn1
Allelic
Composition		 Med23tm1Gwan/Med23tm1Gwan
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Med23tm1Gwan mutation (0 available); any Med23 mutation (73 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal cell differentiation ( J:187746 )
• adipose derived stem cells (ADSCs) infected with a cre expressing adenovirus and exposed to an adipogenic hormone cocktail accumulate fewer lipids and show attenuated expression of adipocyte markers and enhanced expression of smooth muscle cell markers
• differentiation of ADSCs, infected with a cre expressing adenovirus and treated with TGFB, into smooth muscle cells is enhanced




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory