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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gt(ROSA)26Sortm9(Rac1*,-EGFP)Rsky
targeted mutation 9, Klaus Rajewsky
MGI:4430551
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Gt(ROSA)26Sortm9(Rac1*,-EGFP)Rsky/Gt(ROSA)26Sortm9(Rac1*,-EGFP)Rsky
Igh-Jtm1Cgn/Ightm4Cgn
Tg(Cr2-cre)3Cgn/0 		involves: 129P2/OlaHsd * C57BL/6 MGI:4430563
cn2
 		Gt(ROSA)26Sortm9(Rac1*,-EGFP)Rsky/Gt(ROSA)26Sor+
Ptf1atm1(cre)Hnak/Ptf1a+ 		involves: C57BL/6 MGI:5510698


Genotype
MGI:4430563
cn1
Allelic
Composition		 Gt(ROSA)26Sortm9(Rac1*,-EGFP)Rsky/Gt(ROSA)26Sortm9(Rac1*,-EGFP)Rsky
Igh-Jtm1Cgn/Ightm4Cgn
Tg(Cr2-cre)3Cgn/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm9(Rac1*,-EGFP)Rsky mutation (1 available); any Gt(ROSA)26Sor mutation (1046 available)
Igh-Jtm1Cgn mutation (3 available); any Igh-J mutation (12 available)
Ightm4Cgn mutation (0 available); any Igh mutation (45 available)
Tg(Cr2-cre)3Cgn mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased mature B cell number ( J:157297 )
• mice lack mature BCR positive B cells

hematopoietic system
decreased mature B cell number ( J:157297 )
• mice lack mature BCR positive B cells




Genotype
MGI:5510698
cn2
Allelic
Composition		 Gt(ROSA)26Sortm9(Rac1*,-EGFP)Rsky/Gt(ROSA)26Sor+
Ptf1atm1(cre)Hnak/Ptf1a+
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm9(Rac1*,-EGFP)Rsky mutation (1 available); any Gt(ROSA)26Sor mutation (1046 available)
Ptf1atm1(cre)Hnak mutation (1 available); any Ptf1a mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands
endocrine/exocrine gland phenotype ( J:197054 )
N
• mice do not develop acinar to ductal metaplasia

neoplasm
neoplasm ( J:197054 )
N
• mice do not develop pancreatic intraepithelial neoplasia




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory