All Phenotypes Pcyt2<tm1.1Suja> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Pcyt2^tm1.1Suja
targeted mutation 1.1, Suzanne Jackowski
MGI:4415290

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Pcyt2^tm1.1Suja/Pcyt2^tm1.1Suja Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺	involves: C57BL/6 * DBA	MGI:4415291

Allelic Composition	Pcyt2^tm1.1Suja/Pcyt2^tm1.1Suja Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺
Genetic Background	involves: C57BL/6 * DBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pcyt2^tm1.1Suja mutation (0 available); any Pcyt2 mutation (28 available)
Speer6-ps1^{Tg(Alb-cre)21Mgn} mutation (6 available); any Speer6-ps1 mutation (4 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Pcyt2^tm1.1Suja/Pcyt2^tm1.1Suja Speer6-ps1^{Tg(Alb-cre)21Mgn}/0 liver with hepatocytes engorged with lipid droplets

homeostasis/metabolism

decreased circulating triglyceride level ( J:155630 )

increased liver cholesterol level ( J:155630 )

• 2-fold

increased liver triglyceride level ( J:155630 )

• 10-fold

liver/biliary system

increased liver cholesterol level ( J:155630 )

• 2-fold

increased liver triglyceride level ( J:155630 )

• 10-fold

hepatic steatosis ( J:155630 )

pale liver ( J:155630 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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