Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cbltm1Soga mutation
(0 available);
any
Cbl mutation
(57 available)
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immune system
hematopoietic system
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• as determined by colony formation from bone marrow cells in methycellulose culture
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growth/size/body
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cbltm1Soga mutation
(0 available);
any
Cbl mutation
(57 available)
Tg(Tec-BCR/ABL1)5Hhi mutation
(0 available)
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mortality/aging
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• all mice die by 41 weeks after birth with accelerated blast crisis compared to in Tg(BCR/ABL1)5Hhi mice
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immune system
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• mice exhibit enlarged lymph nodes during blastic crisis with massive infiltrates of immature leukemic blasts
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|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cbltm1Soga mutation
(0 available);
any
Cbl mutation
(57 available)
Tg(Tec-BCR/ABL1)5Hhi mutation
(0 available)
|
|
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mortality/aging
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• mice die prematurely with accelerated blast crisis compared to in Tg(BCR/ABL1)5Hhi mice
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