Phenotypes associated with this allele
|
|
| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il4ratm2Tch mutation
(1 available);
any
Il4ra mutation
(41 available)
Tg(Scgb1a1-rtTA,tetO-Il13)1Eli mutation
(0 available)
|
|
|
respiratory system
|
|
• basal airway eosinophilia
|
|
|
• percentage of goblet cells quadruples in mutant mice upon administration of doxycycline as compared to doubling in the control
|
immune system
|
|
• basal airway eosinophilia is increased as compared to Q576 IL-13tg control
• administration of doxycycline amplifies difference
|
|
|
• basal airway eosinophilia
|
hematopoietic system
|
|
• basal airway eosinophilia is increased as compared to Q576 IL-13tg control
• administration of doxycycline amplifies difference
|
|
|
| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Scgb1a1-rtTA,tetO-Il13)1Eli mutation
(0 available)
Tmem219tm1(KOMP)Vlcg mutation
(1 available);
any
Tmem219 mutation
(10 available)
|
|
|
respiratory system
|
|
• increased inflammation, mucus metaplasia and bronchoalveolar lavage fluid in mice sensitized and challenged with ovalbumin
|
|
|
• in mice sensitized and challenged with ovalbumin
|
immune system
|
|
• increased inflammation, mucus metaplasia and bronchoalveolar lavage fluid in mice sensitized and challenged with ovalbumin
|
homeostasis/metabolism
|
|
| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chi3l1tm1Eli mutation
(0 available);
any
Chi3l1 mutation
(26 available)
Tg(Scgb1a1-rtTA,tetO-Il13)1Eli mutation
(0 available)
|
|
|
immune system
|
|
• in mice administered doxycycline, Th2 cell numbers found in the lungs of mice sensitized and challenged with OVA are greater than in wild-type controls but less than in mice carrying just the transgene
|
|
|
• in mice administered doxycycline, Th2 responses to OVA sensitization and challenge to the lungs is greater than wild-type controls but less than in mice carrying just the transgene
|
hematopoietic system
|
|
• in mice administered doxycycline, Th2 cell numbers found in the lungs of mice sensitized and challenged with OVA are greater than in wild-type controls but less than in mice carrying just the transgene
|
|
|
• in mice administered doxycycline, Th2 responses to OVA sensitization and challenge to the lungs is greater than wild-type controls but less than in mice carrying just the transgene
|
|
|
| Find Mice |
Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
|
|
|
immune system
|
|
• in mice administered doxycycline, Th2 cell numbers found in the lungs of mice sensitized and challenged with OVA are much greater than in wild-type controls
|
|
|
• in mice administered doxycycline, Th2 responses to OVA sensitization and challenge to the lungs is greatly exaggerated compared to wild-type controls
|
hematopoietic system
|
|
• in mice administered doxycycline, Th2 cell numbers found in the lungs of mice sensitized and challenged with OVA are much greater than in wild-type controls
|
|
|
• in mice administered doxycycline, Th2 responses to OVA sensitization and challenge to the lungs is greatly exaggerated compared to wild-type controls
|
respiratory system
|
|
• in mice administered doxycycline, pulmonary fibrosis results in the lungs when mice are sensitized and challenged with OVA
|
Analysis Tools