Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il4ratm2Tch mutation
(1 available);
any
Il4ra mutation
(41 available)
Tg(Scgb1a1-rtTA,tetO-Il13)1Eli mutation
(0 available)
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respiratory system
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• basal airway eosinophilia
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• percentage of goblet cells quadruples in mutant mice upon administration of doxycycline as compared to doubling in the control
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immune system
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• basal airway eosinophilia is increased as compared to Q576 IL-13tg control
• administration of doxycycline amplifies difference
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• basal airway eosinophilia
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hematopoietic system
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• basal airway eosinophilia is increased as compared to Q576 IL-13tg control
• administration of doxycycline amplifies difference
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Scgb1a1-rtTA,tetO-Il13)1Eli mutation
(0 available)
Tmem219tm1(KOMP)Vlcg mutation
(1 available);
any
Tmem219 mutation
(10 available)
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respiratory system
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• increased inflammation, mucus metaplasia and bronchoalveolar lavage fluid in mice sensitized and challenged with ovalbumin
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• in mice sensitized and challenged with ovalbumin
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immune system
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• increased inflammation, mucus metaplasia and bronchoalveolar lavage fluid in mice sensitized and challenged with ovalbumin
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homeostasis/metabolism
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chi3l1tm1Eli mutation
(0 available);
any
Chi3l1 mutation
(26 available)
Tg(Scgb1a1-rtTA,tetO-Il13)1Eli mutation
(0 available)
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immune system
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• in mice administered doxycycline, Th2 cell numbers found in the lungs of mice sensitized and challenged with OVA are greater than in wild-type controls but less than in mice carrying just the transgene
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• in mice administered doxycycline, Th2 responses to OVA sensitization and challenge to the lungs is greater than wild-type controls but less than in mice carrying just the transgene
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hematopoietic system
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• in mice administered doxycycline, Th2 cell numbers found in the lungs of mice sensitized and challenged with OVA are greater than in wild-type controls but less than in mice carrying just the transgene
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• in mice administered doxycycline, Th2 responses to OVA sensitization and challenge to the lungs is greater than wild-type controls but less than in mice carrying just the transgene
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
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immune system
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• in mice administered doxycycline, Th2 cell numbers found in the lungs of mice sensitized and challenged with OVA are much greater than in wild-type controls
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• in mice administered doxycycline, Th2 responses to OVA sensitization and challenge to the lungs is greatly exaggerated compared to wild-type controls
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hematopoietic system
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• in mice administered doxycycline, Th2 cell numbers found in the lungs of mice sensitized and challenged with OVA are much greater than in wild-type controls
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• in mice administered doxycycline, Th2 responses to OVA sensitization and challenge to the lungs is greatly exaggerated compared to wild-type controls
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respiratory system
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• in mice administered doxycycline, pulmonary fibrosis results in the lungs when mice are sensitized and challenged with OVA
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