Phenotypes associated with this allele

• Allele Symbol: Actl6a⁺
• Allele Name: wild type
• Allele ID: MGI:2439578
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Actl6a^em1(IMPC)J/Actl6a^+	C57BL/6NJ-Actl6a^em1(IMPC)J/Mmjax	MGI:7266960
cn2	Actl6a^tm1.1Grc/Actl6a^+ Tg(Mx1-cre)1Cgn/0	involves: 129S6/SvEvTac * C57BL/6J * CBA	MGI:5465446

Genotype
MGI:7266960

ht1

• Allelic Composition: Actl6a^em1(IMPC)J/Actl6a⁺
• Genetic Background: C57BL/6NJ-Actl6a^em1(IMPC)J/Mmjax

Data Sources

IMPC Data for Actl6a

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased exploration in new environment ( J:211773 )

♀

IMPC - JAX

hematopoietic system

decreased mean corpuscular hemoglobin ( J:211773 )

IMPC - JAX

homeostasis/metabolism

decreased circulating bilirubin level ( J:211773 )

IMPC - JAX

decreased circulating phosphate level ( J:211773 )

IMPC - JAX

Genotype
MGI:5465446

cn2

• Allelic Composition: Actl6a^tm1.1Grc/Actl6a⁺; Tg(Mx1-cre)1Cgn/0
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * CBA

hematopoietic system

decreased common myeloid progenitor cell number ( J:192124 )

• in the bone marrow of pIpC-treated mice

decreased granulocyte number ( J:192124 )

• in the bone marrow of pIpC-treated mice

decreased macrophage cell number ( J:192124 )

• in the bone marrow of pIpC-treated mice

immune system

decreased granulocyte number ( J:192124 )

• in the bone marrow of pIpC-treated mice

decreased macrophage cell number ( J:192124 )

• in the bone marrow of pIpC-treated mice