skeleton
• phenotype is indistinguishable from mice homozygous null for Lrp5
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• decreased bone formation
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Allele Symbol Allele Name Allele ID |
Creb1+ wild type MGI:2430290 |
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Summary |
5 genotypes
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• phenotype is indistinguishable from mice homozygous null for Lrp5
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• decreased bone formation
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
N |
• loss of expression of 1 copy of Creb1 in osteoblasts rescues the bone phenotype seen in Htrb1 null mice
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• mice did not exhibit any abnormalities
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• no phenotypic or histological abnormalities were detected
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/28/2024 MGI 6.13 |
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