All Phenotypes Sp5<tm1Rbe> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Sp5^tm1Rbe
targeted mutation 1, Rosa Beddington
MGI:1933409

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Sp5^tm1Rbe/Sp5^tm1Rbe	involves: 129P2/Ola * C57BL/6J	MGI:3029241
cx2	Sp5^tm1Rbe/Sp5^tm1Rbe T/T⁺	involves: 129P2/Ola * C57BL/6J	MGI:3029242

Allelic Composition	Sp5^tm1Rbe/Sp5^tm1Rbe
Genetic Background	involves: 129P2/Ola * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sp5^tm1Rbe mutation (0 available); any Sp5 mutation (17 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:65743 )

• mice appear normal up to 1.5 years of age and are fertile

Allelic Composition	Sp5^tm1Rbe/Sp5^tm1Rbe T/T⁺
Genetic Background	involves: 129P2/Ola * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sp5^tm1Rbe mutation (0 available); any Sp5 mutation (17 available)
T mutation (22 available); any T mutation (61 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

decreased caudal vertebrae number ( J:65743 )

• majority of tails are comprised of fewer than 8 vertebrae

short tail ( J:65743 )

skeleton

abnormal vertebrae morphology ( J:65743 )

decreased caudal vertebrae number ( J:65743 )

• majority of tails are comprised of fewer than 8 vertebrae

abnormal lumbar vertebrae morphology ( J:65743 )

• lumbar vertebrae defect consisting of an imperfect fusion of the two ventral halves of the vertebra, resulting in an abnormal centrum

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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