Nxnl2^tm1.2Tlev
Targeted Allele Detail

Summary

• Symbol: Nxnl2^tm1.2Tlev
• Name: nucleoredoxin-like 2; targeted mutation 1.2, Thierry Leveillard
• MGI ID: MGI:5426260
• Gene: Nxnl2 Location: Chr13:51325058-51329224 bp, + strand Genetic Position: Chr13, 26.08 cM, cytoband B1
• Alliance: Nxnl2^tm1.2Tlev page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:183790
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: BALB/c

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cre-mediated recombination of Nxnl2^tm1.1Tlev removed exon 1. (J:183790)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nxnl2 Mutation: 4 strains or lines available

References

• Original: J:183790 Jaillard C, et al., Nxnl2 splicing results in dual functions in neuronal cell survival and maintenance of cell integrity. Hum Mol Genet. 2012 May 15;21(10):2298-311
• All: 3 reference(s)