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Gas5 Gene Detail
Summary
  • Symbol
    Gas5
  • Name
    growth arrest specific 5
  • Synonyms
    Gas-5, Snhg2
Location &
Maps
more
  • Sequence Map
    Chr1:160862171-160866109 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 1, 69.75 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    294 from dbSNP Build 142
  • Strain Annotations
    21
  • PCR
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_95659
lncRNA gene Chr1:160861793-160866118 (+)
129S1/SvImJ ENSMUSG00200007106
lncRNA gene Chr1:158357039-158361163 (+)
A/J ENSMUSG00195023795
lncRNA gene Chr1:157681634-157685755 (+)
AKR/J ENSMUSG00220014415
lncRNA gene Chr1:157472636-157476760 (+)
BALB/cJ ENSMUSG00180034919
protein coding gene Chr1:157912983-157917211 (+)
BALB/cJ ENSMUSG00180039254
lncRNA gene Chr1:157912746-157916861 (+)
C3H/HeJ ENSMUSG00175045486
lncRNA gene Chr1:157992252-157996376 (+)
C57BL/6NJ ENSMUSG00215039765
lncRNA gene Chr1:157880901-157885025 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0013259
unclassified non-coding RNA gene Chr1:151635810-151640057 (+)
CAST/EiJ ENSTCUG00005022094
lncRNA gene Chr1:156514684-156518808 (+)
CBA/J ENSMUSG00210021348
lncRNA gene Chr1:157890016-157894140 (+)
DBA/2J ENSMUSG00185041081
protein coding gene Chr1:162131115-162135343 (+)
DBA/2J ENSMUSG00185046018
lncRNA gene Chr1:162130878-162134993 (+)
FVB/NJ ENSMUSG00205011251
lncRNA gene Chr1:156967692-156971816 (+)
JF1/MsJ ENSUMUG00000024902
lncRNA gene Chr1:161291632-161295747 (+)
LP/J ENSMUSG00230018638
lncRNA gene Chr1:161758428-161762552 (+)
NOD/ShiLtJ ENSMUSG00190041750
lncRNA gene Chr1:157719481-157723605 (+)
NZO/HlLtJ ENSMUSG00225005199
lncRNA gene Chr1:165368768-165372892 (+)
PWK/PhJ ENSLUMG00010043481
lncRNA gene Chr1:156678507-156682617 (+)
SPRET/EiJ ENSMSPG00010044407
lncRNA gene Chr1:160090077-160094216 (+)
WSB/EiJ ENSIUOG00005016388
lncRNA gene Chr1:157278732-157283067 (+)



Homology
more
  • Human Ortholog
    GAS5, growth arrest specific 5
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GAS5, growth arrest specific 5
  • Synonyms
    NCRNA00030, SNHG2
  • Links
    NCBI Gene ID: 60674

  • Chr Location
    1q25.1; chr1:173851424-173869045 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele die during the embryonic period. Heterozygous mice develop osteoporosis and have impaired bone repair capacity.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    • All Sequences
    • RefSeq
    • UniProt
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 14455 NCBI Gene Model | MGI Sequence Detail 3939 C57BL/6J ±  kb
    transcript NR_166052 RefSeq | MGI Sequence Detail 550 C57BL/6  
    polypeptide V9H1D0 UniProt | EBI | MGI Sequence Detail 41 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    Molecular
    Reagents
    less
    • All nucleic 22
      cDNA 14
      Primer pair 7
      Other 1

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGD-MRK-9990, MGD-MRK-9996
    References
    more
    • Summaries
      All 51
      Developmental Gene Expression 12
      Phenotypes 13
    • Earliest
      J:9302 Schneider C, et al., Genes specifically expressed at growth arrest of mammalian cells. Cell. 1988 Sep 9;54(6):787-93
    • Latest
      J:363164 Zhu S, et al., Fine-tuning of Wnt signaling by RNA surveillance factor Smg5 in the mouse craniofacial development. iScience. 2025 Mar 21;28(3):111972

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    09/01/2026
    MGI 6.24
    The Jackson Laboratory