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Aldoa Gene Detail
Summary
  • Symbol
    Aldoa
  • Name
    aldolase A, fructose-bisphosphate
  • Synonyms
    Aldo-1, Aldo1
  • Feature Type
    protein coding gene
  • IDs
    MGI:87994
    NCBI Gene: 11674
  • Alliance
    genome feature page
  • Transcription Start Sites
    19 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:126394406-126399537 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 69.25 cM, cytoband F4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    140 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_87994
 protein coding gene Chr7:126394406-126399923 (-)
129S1/SvImJ ENSMUSG00200024086
 protein coding gene Chr7:112905964-112911481 (-)
A/J ENSMUSG00195042537
 protein coding gene Chr7:117421334-117426864 (-)
AKR/J ENSMUSG00220020261
 protein coding gene Chr7:110854333-110859856 (-)
BALB/cJ ENSMUSG00180012609
 protein coding gene Chr7:114095193-114100716 (-)
C3H/HeJ ENSMUSG00175014047
 protein coding gene Chr7:114822655-114828173 (-)
C57BL/6NJ ENSMUSG00215021810
 protein coding gene Chr7:114102608-114108125 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030466
 protein coding gene Chr7:128813691-128819206 (-)
CAST/EiJ ENSTCUG00005045688
 protein coding gene Chr7:117317638-117323160 (-)
CBA/J ENSMUSG00210022765
 protein coding gene Chr7:114583739-114589256 (-)
DBA/2J ENSMUSG00185048620
 protein coding gene Chr7:118896593-118902111 (-)
FVB/NJ ENSMUSG00205017691
 protein coding gene Chr7:114542153-114547670 (-)
JF1/MsJ ENSUMUG00000020886
 protein coding gene Chr7:123949943-123955466 (-)
LP/J ENSMUSG00230052658
 protein coding gene Chr7:125005958-125011475 (-)
NOD/ShiLtJ ENSMUSG00190012932
 protein coding gene Chr7:114742743-114748263 (-)
NZO/HlLtJ ENSMUSG00225011801
 protein coding gene Chr7:123235264-123240793 (-)
PWK/PhJ ENSLUMG00010031032
 protein coding gene Chr7:113090052-113095569 (-)
SPRET/EiJ ENSMSPG00010009059
 protein coding gene Chr7:114361042-114366519 (-)
WSB/EiJ ENSIUOG00005023689
 protein coding gene Chr7:115444560-115450090 (-)



Homology
more
  • Human Ortholog
    ALDOA, aldolase, fructose-bisphosphate A
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ALDOA, aldolase, fructose-bisphosphate A
  • Synonyms
    ALDA, GSD12, HEL-S-87p
  • Links
    NCBI Gene ID: 226
    UniProt: P04075

  • Chr Location
    16p11.2; chr16:30064164-30070457 (+)  GRCh38
Human Diseases
less
  • References
    3 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    58 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    53
  • GO References
    22
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    904
  • Tissues
    203
  • cDNA Data
    1045
  • Literature Summary
    32
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 11674 NCBI Gene Model | MGI Sequence Detail 5132 C57BL/6J ±  kb
transcript NM_001177307 RefSeq | MGI Sequence Detail 1595 C57BL/6  
polypeptide P05064 UniProt | EBI | MGI Sequence Detail 364 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 1054
    Genomic 2
    cDNA 1045
    Primer pair 6
    Other 1

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-1276, MGD-MRK-1278
References
more
  • Summaries
    All 147
    Developmental Gene Expression 32
    Diseases 3
    Gene Ontology 22
    Phenotypes 58
  • Earliest
    J:21434 Paolella G, et al., Structure and expression of mouse aldolase genes. Brain-specific aldolase C amino acid sequence is closely related to aldolase A. Eur J Biochem. 1986 Apr 15;156(2):229-35
  • Latest
    J:389705 Hao L, et al., Heart rate and sleep history encode ultradian REM sleep timing. Curr Biol. 2026 Mar 23;36(6):1422-1434.e5
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory