Sequence Detail

ID/Version

P05064 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2026-06-10

Sequence description from provider

RecName: Full=Fructose-bisphosphate aldolase A; EC=4.1.2.13 {ECO:0000269|PubMed:28723898};AltName: Full=Aldolase 1;AltName: Full=Muscle-type aldolase;

Provider

SWISS-PROT

Sequence

Polypeptide 364 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Aldoa	aldolase A, fructose-bisphosphate	53	121	4	12

Sequence references in MGI

J:8993 Mestek A, et al., Sequence of a mouse brain aldolase A cDNA. Nucleic Acids Res. 1987 Dec 23;15(24):10595
J:10607 Stauffer JK, et al., Nonconservative utilization of aldolase A alternative promoters. J Biol Chem. 1990 Jul 15;265(20):11773-82
J:21434 Paolella G, et al., Structure and expression of mouse aldolase genes. Brain-specific aldolase C amino acid sequence is closely related to aldolase A. Eur J Biochem. 1986 Apr 15;156(2):229-35
J:253142 Zhang CS, et al., Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK. Nature. 2017 Aug 3;548(7665):112-116
J:282006 Li M, et al., Transient Receptor Potential V Channels Are Essential for Glucose Sensing by Aldolase and AMPK. Cell Metab. 2019 Sep 3;30(3):508-524.e12
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:371190 Lin J, et al., A microbial amino-acid-conjugated bile acid, tryptophan-cholic acid, improves glucose homeostasis via the orphan receptor MRGPRE. Cell. 2025 Aug 21;188(17):4530-4548.e25