Myl2 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:279716 Braitsch CM, et al., LATS1/2 suppress NFkappaB and aberrant EMT initiation to permit pancreatic progenitor differentiation. PLoS Biol. 2019 Jul;17(7):e3000382
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:8352275
Gene symbol:	Myl2
Gene name:	myosin, light polypeptide 2, regulatory, cardiac, slow

Antibody:	anti-phospho-myosin light chain II (Ser19) (3675)
Detection system:	Secondary antibody coupled to Alexa Fluor

Results

S4E WT lower ©

S4E WT upper ©

Specimen S4E WT: embryonic day 12.5 (more

)
Note: Controls were either wild type or heterozygous littermates. Triple labeled: green - Myl2; magenta - Lamc1 (assay MGI:8351675); red - Muc1 (assay MGI:8346383).

Structure	Level	Pattern	Image	Note
TS20: pancreas epithelium	Present		S4E WT upper , S4E WT lower

Specimen S4E Lats1/2^PanKO: embryonic day 12.5; Lats1^tm1.1Jfm/Lats1^tm1.1Jfm, Lats2^tm1.1Jfm/Lats2^tm1.1Jfm, Tg(Pdx1-cre)89.1Dam/0 (more

)
Note: Conditional mutant. Triple labeled: green - Myl2; magenta - Lamc1 (assay MGI:8351675); red - Muc1 (assay MGI:8346383).

Structure	Level	Pattern	Image	Note
TS20: pancreas epithelium	Ambiguous		S4E Lats1/2^PanKO upper , S4E Lats1/2^PanKO lower	Staining was absent at the apical membrane of pancreatic epithelial cells.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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