Lamc1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:279716 Braitsch CM, et al., LATS1/2 suppress NFkappaB and aberrant EMT initiation to permit pancreatic progenitor differentiation. PLoS Biol. 2019 Jul;17(7):e3000382
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:8351675
Gene symbol:	Lamc1
Gene name:	laminin, gamma 1

Antibody:	Anti-LAMC1
Detection system:	Secondary antibody coupled to Alexa Fluor

Results

S2C WT ©

Specimen S2C WT: embryonic day 12.5 (more

)
Note: Controls were either wild type or heterozygous littermates. Double labeled: green - Lamc1; red - Ctnnb1 (assay MGI:8351284).

Structure	Level	Pattern	Image	Note
TS20: pancreas	Present	Non-Uniform	S2C WT

S2C Lats1/2/Yap1^PanKOTaz^Het ©

Specimen S2C Lats1/2/Yap1^PanKOTaz^Het: embryonic day 12.5; Lats1^tm1.1Jfm/Lats1^tm1.1Jfm, Lats2^tm1.1Jfm/Lats2^tm1.1Jfm, Tg(Pdx1-cre)89.1Dam/0, Wwtr1^tm1.1Eno/Wwtr1⁺, Yap1^tm1.1Eno/Yap1^tm1.1Eno (more

)
Note: Conditional mutant. Double labeled: green - Lamc1; red - Ctnnb1 (assay MGI:8351284).

Structure	Level	Pattern	Image	Note
TS20: pancreas	Present	Non-Uniform	S2C Lats1/2/Yap1^PanKOTaz^Het	Normal expression was detected in Lats1/2/Yap1<PanKO>Taz<Het> mice.

S2C Lats1/2^PanKO ©

Specimen S2C Lats1/2^PanKO: embryonic day 12.5; Lats1^tm1.1Jfm/Lats1^tm1.1Jfm, Lats2^tm1.1Jfm/Lats2^tm1.1Jfm, Tg(Pdx1-cre)89.1Dam/0 (more

)
Note: Conditional mutant. Double labeled: green - Lamc1; red - Ctnnb1 (assay MGI:8351284).

Structure	Level	Pattern	Image	Note
TS20: pancreas	Present	Non-Uniform	S2C Lats1/2^PanKO

S4E WT lower ©

S4E WT upper ©

Specimen S4E WT: embryonic day 12.5 (more

)
Note: Controls were either wild type or heterozygous littermates. Triple labeled: magenta - Lamc1; red - Muc1 (assay MGI:8346383); green - Myl2 (assay MGI:8352275).

Structure	Level	Pattern	Image	Note
TS20: pancreas	Present		S4E WT lower , S4E WT upper

Specimen S4E Lats1/2^PanKO: embryonic day 12.5; Lats1^tm1.1Jfm/Lats1^tm1.1Jfm, Lats2^tm1.1Jfm/Lats2^tm1.1Jfm, Tg(Pdx1-cre)89.1Dam/0 (more

)
Note: Conditional mutant. Triple labeled: magenta - Lamc1; red - Muc1 (assay MGI:8346383); green - Myl2 (assay MGI:8352275).

Structure	Level	Pattern	Image	Note
TS20: pancreas	Present		S4E Lats1/2^PanKO upper , S4E Lats1/2^PanKO lower

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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