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Gene Expression Data
Assay Details
Assay
Reference: J:181272 Le TT, et al., Requirements for Jag1-Rbpj mediated Notch signaling during early mouse lens development. Dev Dyn. 2012 Mar;241(3):493-504
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8172376
Gene symbol: Cdh1
Gene name: cadherin 1
Antibody: anti-E-cadherin/CDH1 (ECCD-2)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 3A: postnatal day 0; Jag1tm1Jlew/Jag1tm1Jlew (more )
Note: Double labeled: green - Cdh1; red - Cdkn1c (assay MGI:8172381).
Structure Level Pattern Image Note
TS27: lens anterior epithelium Present 3A
Specimen 3B: postnatal day 0; Jag1tm1Jlew/Jag1+, Tfap2atm1(cre)Moon/Tfap2a+ (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - Cdkn1c (assay MGI:8172381).
Structure Level Pattern Image Note
TS27: lens anterior epithelium Present 3B Similar as in the control.
Specimen 3C: postnatal day 0; Jag1tm1Jlew/Jag1tm1Jlew, Tfap2atm1(cre)Moon/Tfap2a+ (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - Cdkn1c (assay MGI:8172381).
Structure Level Pattern Image Note
TS27: lens anterior epithelium Present 3C Reduced expression in anterior epithelial layer with a smaller lens size.
Specimen 3G: embryonic day 14.5; Rbpjtm1Hon/Rbpjtm1Hon (more )
Note: Double labeled: green - Cdh1; red - Foxe3 (assay MGI:8172382).
Structure Level Pattern Image Note
TS22: lens anterior epithelium Present 3G Coexpressed with Foxe3.
Specimen 3H: embryonic day 14.5; Rbpjtm1Hon/Rbpj+, Tfap2atm1(cre)Moon/Tfap2a+ (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - Foxe3 (assay MGI:8172382).
Structure Level Pattern Image Note
TS22: lens anterior epithelium Present 3H Coexpressed with Foxe3, similar as in the control.
Specimen 3I: embryonic day 14.5; Rbpjtm1Hon/Rbpjtm1Hon, Tfap2atm1(cre)Moon/Tfap2a+ (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - Foxe3 (assay MGI:8172382).
Structure Level Pattern Image Note
TS22: lens anterior epithelium Weak 3I A severely reduced lenses with very few Cdh1+Foxe3+ cells.
Specimen 4A: embryonic day 11.5; Rbpjtm1Hon/Rbpjtm1Hon (more )
Note: Double labeled: green - Cdh1; red - Maf (assay MGI:8172383).
Structure Cell Type Level Pattern Image Note
TS19: lens vesicle anterior epithelium anterior lens cell Present 4A
Specimen 4B: embryonic day 11.5; Rbpjtm1Hon/Rbpj+, Tfap2atm1(cre)Moon/Tfap2a+ (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - Maf (assay MGI:8172383).
Structure Cell Type Level Pattern Image Note
TS19: lens vesicle anterior epithelium anterior lens cell Present 4B Similar as in the control.
Specimen 4C: embryonic day 11.5; Rbpjtm1Hon/Rbpjtm1Hon, Tfap2atm1(cre)Moon/Tfap2a+ (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - Maf (assay MGI:8172383).
Structure Level Pattern Image Note
TS19: lens vesicle anterior epithelium Present 4C The lens vesicle was abnormally small with a persistent connection to the surface ectoderm by means of a Cdh1+ lens stalk.
Specimen 4D: embryonic day 11.0; Jag1tm1Jlew/Jag1tm1Jlew (more )
Note: Double labeled: green - Cdh1; red - Cdkn1c (assay MGI:8172381).
Structure Level Pattern Image Note
TS18: lens vesicle epithelium Present Regionally restricted 4D Expressed in the anterior progenitor cells.
Specimen 4E: embryonic day 11.0; Jag1tm1Jlew/Jag1+, Tfap2atm1(cre)Moon/Tfap2a+ (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - Cdkn1c (assay MGI:8172381).
Structure Level Pattern Image Note
TS18: lens vesicle epithelium Present Regionally restricted 4E Expressed in the anterior progenitor cells, similar as in the control.
Specimen 4F: embryonic day 11.0; Jag1tm1Jlew/Jag1tm1Jlew, Tfap2atm1(cre)Moon/Tfap2a+ (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - Cdkn1c (assay MGI:8172381).
Structure Level Pattern Image Note
TS18: lens vesicle epithelium Present Regionally restricted 4F Expressed in the anterior progenitor cells. The lens vesicle was abnormally small with a persistent connection to the surface ectoderm by means of a Cdh1+ lens stalk.
Specimen 4J: embryonic day 15.5; Jag1tm1Jlew/Jag1tm1Jlew (more )
Note: Double labeled: green - Cdh1; red - Cryba1 (assay MGI:8172406).
Structure Level Pattern Image Note
TS23: lens anterior epithelium Present 4J
Specimen 4K: embryonic day 15.5; Jag1tm1Jlew/Jag1+, Tfap2atm1(cre)Moon/Tfap2a+ (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - Cryba1 (assay MGI:8172406).
Structure Level Pattern Image Note
TS23: lens anterior epithelium Present 4K Similar as in the control.
Specimen 4L: embryonic day 15.5; Jag1tm1Jlew/Jag1tm1Jlew, Tfap2atm1(cre)Moon/Tfap2a+ (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - Cryba1 (assay MGI:8172406).
Structure Level Pattern Image Note
TS23: lens anterior epithelium Present 4L The lens vesicle was abnormally small with a persistent connection to the surface ectoderm by means of a Cdh1+ lens stalk.
Specimen 5K: embryonic day 11.5; Gt(ROSA)26Sortm1(Notch1)Dam/Gt(ROSA)26Sortm1(Notch1)Dam (more )
Note: Double labeled: green - Cdh1; red - Prox1 (assay MGI:8172426).
Structure Cell Type Level Pattern Image Note
TS19: lens vesicle anterior epithelium anterior lens cell Present 5K
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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