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Gene Expression Data
Assay Details
Assay
Reference: J:181272 Le TT, et al., Requirements for Jag1-Rbpj mediated Notch signaling during early mouse lens development. Dev Dyn. 2012 Mar;241(3):493-504
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8172406
Gene symbol: Cryba1
Gene name: crystallin, beta A1
Antibody: beta-crystallin antibody
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 4J: embryonic day 15.5; Jag1tm1Jlew/Jag1tm1Jlew (more )
Note: Double labeled: red - Cryba1; green - Cdh1 (assay MGI:8172376).
Structure Cell Type Level Pattern Image Note
TS23: lens fiber lens fiber cell Present 4J
Specimen 4K: embryonic day 15.5; Jag1tm1Jlew/Jag1+, Tfap2atm1(cre)Moon/Tfap2a+ (more )
Note: Conditional mutant. Double labeled: red - Cryba1; green - Cdh1 (assay MGI:8172376).
Structure Cell Type Level Pattern Image Note
TS23: lens fiber lens fiber cell Present 4K Similar as in the control.
Specimen 4L: embryonic day 15.5; Jag1tm1Jlew/Jag1tm1Jlew, Tfap2atm1(cre)Moon/Tfap2a+ (more )
Note: Conditional mutant. Double labeled: red - Cryba1; green - Cdh1 (assay MGI:8172376).
Structure Cell Type Level Pattern Image Note
TS23: lens fiber lens fiber cell Present 4L Abnormal extrusion of positive lens tissue into the anterior chamber or the mesenchymal space around the persistent lens stalk was seen.
Specimen not shown: embryonic day 15.5; Rbpjtm1Hon/Rbpjtm1Hon, Tfap2atm1(cre)Moon/Tfap2a+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS23: lens fiber lens fiber cell Present Abnormal extrusion of positive lens tissue into the anterior chamber or the mesenchymal space around the persistent lens stalk was seen.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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