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Gene Expression Data
Assay Details
Assay
Reference: J:355262 Kadhim AZ, et al., Transcriptional coactivator MED15 is required for beta cell maturation. Nat Commun. 2024 Oct 8;15(1):8711
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8166935
Gene symbol: Gcg
Gene name: glucagon
Antibody: anti-Gcg
Results
Specimen 1B Gcg: embryonic day 13.5 (more )
Note: Triple labeled: white - Gcg; red - Ins1 (assay MGI:8166934) and Ins2 (assay MGI:8166967); green - Med15 (assay MGI:8166933).
Structure Cell Type Level Pattern Image Note
TS21: pancreas pancreatic A cell Present 1B (upper) Expression in alpha-cells.
Specimen 1C Gcg: embryonic day 18.5 (more )
Note: Triple labeled: white - Gcg; red - Ins1 (assay MGI:8166934) and Ins2 (assay MGI:8166967); green - Med15 (assay MGI:8166933).
Structure Cell Type Level Pattern Image Note
TS26: pancreas pancreatic A cell Present 1C (upper) Expression in alpha-cells.
Specimen 1D Gcg: postnatal week 8 (more )
Note: Triple labeled: white - Gcg; red - Ins1 (assay MGI:8166934) and Ins2 (assay MGI:8166967); green - Med15 (assay MGI:8166933).
Structure Cell Type Level Pattern Image Note
TS28: pancreas pancreatic A cell Present 1D (upper) Expression in alpha-cells.
Specimen S3F CTRL Gcg: postnatal week 8; Ins1tm1.1(cre)Thor/Ins1+ (more )
Note: Double labeled: red - Gcg; green - Ins1 (assay MGI:8166934) and Ins2 (assay MGI:8166967).
Structure Level Pattern Image Note
TS28: pancreas Present S3F CTRL
Specimen S3F M15betaKO Gcg: postnatal week 8; Ins1tm1.1(cre)Thor/Ins1+, Med15tm1c(KOMP)Wtsi/Med15tm1c(KOMP)Wtsi (more )
Note: Conditional mutant. Double labeled: red - Gcg; green - Ins1 (assay MGI:8166934) and Ins2 (assay MGI:8166967).
Structure Level Pattern Image Note
TS28: pancreas Present S3F M15betaKO Authors report no change in alpha-cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/06/2026
MGI 6.29 		The Jackson Laboratory