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Gene Expression Data
Assay Details
Assay
Reference: J:284490 Varum S, et al., Yin Yang 1 Orchestrates a Metabolic Program Required for Both Neural Crest Development and Melanoma Formation. Cell Stem Cell. 2019 Apr 4;24(4):637-653.e9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7332915
Gene symbol: Nefm
Gene name: neurofilament, medium polypeptide
Antibody: anti-NF160 antibody (clone NN18) (N5264 or MAB5254)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen S1D Control: embryonic day 11.5; Yy1tm2Yshi/Yy1+ (more )
Note: Control could be Yy1fl/+; Yy1fl/fl or Yy1fl/+;Wnt1-Cre.
Structure Level Pattern Image Note
TS19: enteric nervous system Present S1D Control
Specimen S1D Yy1 cko: embryonic day 11.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Yy1tm2Yshi/Yy1tm2Yshi (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: enteric nervous system Absent S1D Yy1 cko
Specimen 1K Control: embryonic day 13.5; Yy1tm2Yshi/Yy1+ (more )
Note: Control could be Yy1fl/+; Yy1fl/fl or Yy1fl/+;Wnt1-Cre.
Structure Level Pattern Image Note
TS21: enteric nervous system Present 1K Control
Specimen 1K Yy1 cko: embryonic day 13.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Yy1tm2Yshi/Yy1tm2Yshi (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: enteric nervous system Absent 1K Yy1 cko
Specimen S1E Control: embryonic day 11.5; Yy1tm2Yshi/Yy1+ (more )
Note: Control could be Yy1fl/+; Yy1fl/fl or Yy1fl/+;Wnt1-Cre. Double labeled: green - Nefm; red - Brn3a (Pou4f1 assay MGI:7332923).
Structure Level Pattern Image Note
TS19: dorsal root ganglion Present S1E Control
Specimen S1E Yy1 cko: embryonic day 11.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Yy1tm2Yshi/Yy1tm2Yshi (more )
Note: Conditional mutant. Double labeled: green - Nefm; red - Brn3a (Pou4f1 assay MGI:7332923).
Structure Level Pattern Image Note
TS19: dorsal root ganglion Weak S1E Yy1 cko Reduction in size of dorsal root ganglia.
Specimen 1N Control: embryonic day 13.5; Yy1tm2Yshi/Yy1+ (more )
Note: Control could be Yy1fl/+; Yy1fl/fl or Yy1fl/+;Wnt1-Cre. Double labeled: green - Nefm; red - Brn3a (Pou4f1 assay MGI:7332923).
Structure Level Pattern Image Note
TS21: dorsal root ganglion Present 1N Control
Specimen 1N Yy1 cko: embryonic day 13.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Yy1tm2Yshi/Yy1tm2Yshi (more )
Note: Conditional mutant. Double labeled: green - Nefm; red - Brn3a (Pou4f1 assay MGI:7332923).
Structure Level Pattern Image Note
TS21: dorsal root ganglion Weak 1N Yy1 cko Reduction in size of dorsal root ganglia.
Specimen S1G Control: embryonic day 11.5; Yy1tm2Yshi/Yy1+ (more )
Note: Control could be Yy1fl/+; Yy1fl/fl or Yy1fl/+;Wnt1-Cre. Double labeled: green - Nefm; red - Sox10 (assay MGI:7332913).
Structure Level Pattern Image Note
TS19: dorsal root ganglion Present S1G Control
Specimen S1G Yy1 cko: embryonic day 11.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Yy1tm2Yshi/Yy1tm2Yshi (more )
Note: Conditional mutant. Double labeled: green - Nefm; red - Sox10 (assay MGI:7332913).
Structure Level Pattern Image Note
TS19: dorsal root ganglion Weak S1G Yy1 cko Reduction in size of dorsal root ganglia.
Specimen 1O Control: embryonic day 13.5; Yy1tm2Yshi/Yy1+ (more )
Note: Control could be Yy1fl/+; Yy1fl/fl or Yy1fl/+;Wnt1-Cre. Double labeled: green - Nefm; red - Sox10 (assay MGI:7332913).
Structure Level Pattern Image Note
TS21: dorsal root ganglion Present 1O Control
Specimen 1O Yy1 cko: embryonic day 13.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Yy1tm2Yshi/Yy1tm2Yshi (more )
Note: Conditional mutant. Double labeled: green - Nefm; red - Sox10 (assay MGI:7332913).
Structure Level Pattern Image Note
TS21: dorsal root ganglion Weak 1O Yy1 cko Reduction in size of dorsal root ganglia.
Specimen 2E Control: embryonic day 11.5; Yy1tm2Yshi/Yy1+ (more )
Note: Control could be Yy1fl/+; Yy1fl/fl or Yy1fl/+;Wnt1-Cre. Double labeled: green - Nefm; red - Edu.
Structure Level Pattern Image Note
TS19: dorsal root ganglion Present 2E Control
Specimen 2E Yy1 cko: embryonic day 11.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Yy1tm2Yshi/Yy1tm2Yshi (more )
Note: Conditional mutant. Double labeled: green - Nefm; red - Edu.
Structure Level Pattern Image Note
TS19: dorsal root ganglion Present 2E Yy1 cko
Specimen 2F Control: embryonic day 13.5; Yy1tm2Yshi/Yy1+ (more )
Note: Control could be Yy1fl/+; Yy1fl/fl or Yy1fl/+;Wnt1-Cre. Double labeled: green - Nefm; red - Edu.
Structure Level Pattern Image Note
TS21: dorsal root ganglion Present 2F Control
Specimen 2F Yy1 cko: embryonic day 13.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Yy1tm2Yshi/Yy1tm2Yshi (more )
Note: Conditional mutant. Double labeled: green - Nefm; red - Edu.
Structure Level Pattern Image Note
TS21: dorsal root ganglion Present 2F Yy1 cko
Specimen 2H Control: embryonic day 11.5; Yy1tm2Yshi/Yy1+ (more )
Note: Control could be Yy1fl/+; Yy1fl/fl or Yy1fl/+;Wnt1-Cre. Double labeled: green - Nefm; red - Casp3 (assay MGI:7332926).
Structure Level Pattern Image Note
TS19: dorsal root ganglion Present 2H Control
Specimen 2H Yy1 cko: embryonic day 11.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Yy1tm2Yshi/Yy1tm2Yshi (more )
Note: Conditional mutant. Double labeled: green - Nefm; red - Casp3 (assay MGI:7332926).
Structure Level Pattern Image Note
TS19: dorsal root ganglion Present 2H Yy1 cko
Specimen 2I Control: embryonic day 13.5; Yy1tm2Yshi/Yy1+ (more )
Note: Control could be Yy1fl/+; Yy1fl/fl or Yy1fl/+;Wnt1-Cre. Double labeled: green - Nefm; red - Casp3 (assay MGI:7332926).
Structure Level Pattern Image Note
TS21: dorsal root ganglion Present 2I Control
Specimen 2I Yy1 cko: embryonic day 13.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Yy1tm2Yshi/Yy1tm2Yshi (more )
Note: Conditional mutant. Double labeled: green - Nefm; red - Casp3 (assay MGI:7332926).
Structure Level Pattern Image Note
TS21: dorsal root ganglion Present 2I Yy1 cko
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03/18/2025
MGI 6.24 		The Jackson Laboratory