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Gene Expression Data
Assay Details
Assay
Reference: J:158780 Li S, et al., SEL1L deficiency impairs growth and differentiation of pancreatic epithelial cells. BMC Dev Biol. 2010;10:19
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6479964
Gene symbol: Ins1
Gene name: insulin I
Antibody: anti-insulin
Results
Specimen 1D: embryonic day 12.5; Sel1lGt(CA0017)Wtsi/Sel1l+ (more )
Note: Double labeled: green - Ins1 and Ins2; red - Sel1l reporter (assay MGI:6479960).
Structure Level Pattern Image Note
TS20: pancreas epithelium Present Regionally restricted 1D Expression in endocrine lineage.

Specimen 1J: embryonic day 15.5; Sel1lGt(CA0017)Wtsi/Sel1l+ (more )
Note: Double labeled: green - Ins1 and Ins2; red - Sel1l reporter (assay MGI:6479960).
Structure Level Pattern Image Note
TS23: endocrine pancreas Present 1J

Specimen 2C: embryonic day 13.5 (more )
Note: Double labeled: red - Ins1 and Ins2; green - Pdx1 (assay MGI:6479966).
Structure Level Pattern Image Note
TS21: pancreas epithelium Ambiguous 2C

Specimen 2D: embryonic day 13.5; Sel1lGt(CA0017)Wtsi/Sel1lGt(CA0017)Wtsi (more )
Note: Double labeled: red - Ins1 and Ins2; green - Pdx1 (assay MGI:6479966).
Structure Level Pattern Image Note
TS21: pancreas epithelium Ambiguous 2D

Specimen 3E: embryonic day 15.5 (more )
Note: Double labeled: red - Ins1 and Ins2; green - Amy (assay MGI:6479967).
Structure Level Pattern Image Note
TS23: endocrine pancreas Present Regionally restricted 3E Expression in beta cells. Significant numbers of expressing cells detected.

Specimen 3F: embryonic day 15.5; Sel1lGt(CA0017)Wtsi/Sel1lGt(CA0017)Wtsi (more )
Note: Double labeled: red - Ins1 and Ins2; green - Amy (assay MGI:6479967).
Structure Level Pattern Image Note
TS23: endocrine pancreas Weak Regionally restricted 3F Markedly reduced number of expressing cells compared to wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory