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Sel1lGt(CA0017)Wtsi
Gene trapped Allele Detail
Summary
Symbol: Sel1lGt(CA0017)Wtsi
Name: sel-1 suppressor of lin-12-like (C. elegans); gene trap CA0017, Wellcome Trust Sanger Institute
MGI ID: MGI:3864670
Synonyms: Sel1lbetageo
Gene: Sel1l  Location: Chr12:91772817-91815931 bp, - strand  Genetic Position: Chr12, 45.02 cM, cytoband E
Alliance: Sel1lGt(CA0017)Wtsi page
Impaired pancreatic epithelial growth and branching morphogenesis in Sel1lGt(CA0017)Wtsi/Sel1lGt(CA0017)Wtsi embryos

Show the 4 phenotype image(s) involving this allele.

Mutation
origin
Mutant Cell Line:  CA0017
Germline Transmission:  Earliest citation of germline transmission: J:158780
Parent Cell Line:  E14TG2a.4 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Sanger Inst. Gene Trap Res.
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: pGT0lxf*
 
Mutation detailsThe gene trap vector inserted into the 14th intron. Beta-galactosidase expression was detected in islet and acinar cells. The fusion peptide lacks the Hrd3-like motif, the transmembrane domain, the proline-rich domain, and 4 Sel1lL-like repeats. (J:158780)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Generation of the Sel1lGt(CA0017)Wtsi allele
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 58 assay results
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sel1l Mutation:  32 strains or lines available
References
Original:  J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008;
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory