About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:158780 Li S, et al., SEL1L deficiency impairs growth and differentiation of pancreatic epithelial cells. BMC Dev Biol. 2010;10:19
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6479960
Gene symbol: Sel1l
Gene name: sel-1 suppressor of lin-12-like (C. elegans)
Reporter: lacZ
Antibody: anti-B-galactosidase
Results
Specimen 1A: embryonic day 12.5; Sel1lGt(CA0017)Wtsi/Sel1l+ (more )
Note: Double labeled: red - Sel1l reporter; green - Sox9 (assay MGI:6479962).
Structure Level Pattern Image Note
TS20: pancreas epithelium Present Regionally restricted 1A Expression in small number of cells within core of Sox9-expressing pancreatic epithelium.
Specimen 1B: embryonic day 12.5; Sel1lGt(CA0017)Wtsi/Sel1l+ (more )
Note: Double labeled: red - Sel1l reporter; green - Sox9 (assay MGI:6479962).
Structure Level Pattern Image Note
TS20: pancreas epithelium Present Regionally restricted 1B No co-expression with Sox9.
Specimen 1C: embryonic day 12.5; Sel1lGt(CA0017)Wtsi/Sel1l+ (more )
Note: Double labeled: red - Sel1l reporter; green - Glu (Gcg assay MGI:6479963).
Structure Level Pattern Image Note
TS20: pancreas epithelium Present Regionally restricted 1C Co-expression with glucagon.
Specimen 1D: embryonic day 12.5; Sel1lGt(CA0017)Wtsi/Sel1l+ (more )
Note: Double labeled: red - Sel1l reporter; green - Ins1 (assay MGI:6479964) and Ins2 (assay MGI:6479965).
Structure Level Pattern Image Note
TS20: pancreas epithelium Present Regionally restricted 1D Co-expression with insulin.
Specimen 1E: embryonic day 14.5; Sel1lGt(CA0017)Wtsi/Sel1l+ (more )
Note: Double labeled: red - Sel1l reporter; green - Pdx1 (assay MGI:6479966).
Structure Level Pattern Image Note
TS22: pancreas epithelium Present Graded 1E High expression in epithelial branches; no or very low expression in core "duct-like" epithelium.
Specimen 1F: embryonic day 14.5; Sel1lGt(CA0017)Wtsi/Sel1l+ (more )
Note: Double labeled: red - Sel1l reporter; green - Sox9 (assay MGI:6479962).
Structure Level Pattern Image Note
TS22: pancreas epithelium Present Regionally restricted 1F Very low expression in core epithelial cells expressing Sox9.
Specimen 1G: embryonic day 15.5; Sel1lGt(CA0017)Wtsi/Sel1l+ (more )
Note: Double labeled: red - Sel1l reporter; green - Amy (assay MGI:6479967).
Structure Level Pattern Image Note
TS23: pancreas epithelium Strong Regionally restricted 1G High expression in core pancreatic epithelium.
Specimen 1H: embryonic day 15.5; Sel1lGt(CA0017)Wtsi/Sel1l+ (more )
Note: Double labeled: red - Sel1l reporter; green - Amy (assay MGI:6479967).
Structure Level Pattern Image Note
TS23: pancreas epithelium Strong Regionally restricted 1H High expression in core pancreatic epithelium.
Specimen 1I: embryonic day 15.5; Sel1lGt(CA0017)Wtsi/Sel1l+ (more )
Note: Double labeled: red - Sel1l reporter; green - Glu (Gcg assay MGI:6479963).
Structure Level Pattern Image Note
TS23: pancreas epithelium Present Regionally restricted 1I Expression co-localizes with glucagon.
Specimen 1J: embryonic day 15.5; Sel1lGt(CA0017)Wtsi/Sel1l+ (more )
Note: Double labeled: red - Sel1l reporter; green - Ins1 (assay MGI:6479964) and Ins2 (assay MGI:6479965).
Structure Level Pattern Image Note
TS23: pancreas epithelium Present Regionally restricted 1J Expression co-localizes with insulin.
Specimen 1K: postnatal day 1; Sel1lGt(CA0017)Wtsi/Sel1l+ (more )
Note: Double labeled: red - Sel1l reporter; green - Glu (Gcg assay MGI:6479963).
Structure Level Pattern Image Note
TS27: islets of Langerhans Present 1K Expression in both islet and acinar cells.
TS27: pancreatic acinus Present 1K Expression in both islet and acinar cells.
Specimen 1L: postnatal day 1; Sel1lGt(CA0017)Wtsi/Sel1l+ (more )
Note: Double labeled: red - Sel1l reporter; green - Pdx1 (assay MGI:6479966).
Structure Level Pattern Image Note
TS27: islets of Langerhans Present Regionally restricted 1L Expression co-localizes with Pdx1 in islet cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory