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Gene Expression Data
Assay Details
Assay
Reference: J:132598 Nishimura W, et al., Preferential reduction of beta cells derived from Pax6-MafB pathway in MafB deficient mice. Dev Biol. 2008 Feb 15;314(2):443-56
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6382866
Gene symbol: Gcg
Gene name: glucagon
Antibody: anti-glucagon
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to Texas Red
Results
Specimen 3A: embryonic day 12.5 (more )
Note: Double labeled: red - Gluc (Gcg); green - Nkx6-1 (assay MGI:6382861).
Structure Level Pattern Image Note
TS20: pancreas Present 3A
Specimen 3B: embryonic day 12.5 (more )
Note: Double labeled: red - Gluc (Gcg); green - Pdx1 (assay MGI:6382863).
Structure Level Pattern Image Note
TS20: pancreas Present 3B
Specimen 3C: embryonic day 12.5 (more )
Note: Double labeled: red - Gluc (Gcg); green - Mafb (assay MGI:6382862).
Structure Level Pattern Image Note
TS20: pancreas Present 3C
Specimen 3D: embryonic day 15.5 (more )
Note: Double labeled: red - Gluc (Gcg); green - Mafb (assay MGI:6382862).
Structure Level Pattern Image Note
TS23: pancreas Present 3D
Specimen 3E: embryonic day 12.5; Pax6Sey-Neu/Pax6+ (more )
Note: Double labeled: red - Gluc (Gcg); green - Nkx6-1 (assay MGI:6382861).
Structure Level Pattern Image Note
TS20: pancreas Weak 3E Expression reduced compared with wild type.
Specimen 3F: embryonic day 12.5; Pax6Sey-Neu/Pax6+ (more )
Note: Double labeled: red - Gluc (Gcg); green - Pdx1 (assay MGI:6382863).
Structure Level Pattern Image Note
TS20: pancreas Weak 3F Expression reduced compared with wild type.
Specimen 3G: embryonic day 12.5; Pax6Sey-Neu/Pax6+ (more )
Note: Double labeled: red - Gluc (Gcg); green - Mafb (assay MGI:6382862).
Structure Level Pattern Image Note
TS20: pancreas Weak 3G Expression reduced compared with wild type.
Specimen 3H: embryonic day 15.5; Pax6Sey-Neu/Pax6+ (more )
Note: Double labeled: red - Gluc (Gcg); green - Mafb (assay MGI:6382862).
Structure Level Pattern Image Note
TS23: pancreas Weak 3H Expression reduced compared with wild type.
Specimen S2A: embryonic day 15.5 (more )
Note: Double labeled: red - Gcg and Ins1 (assay MGI:6382865) and Ins2 (assay MGI:6382879); green - Ghrl (assay MGI:6382721).
Structure Level Pattern Image Note
TS23: pancreas Present S2A
Specimen S2B: embryonic day 15.5; Pax6Sey-Neu/Pax6+ (more )
Note: Double labeled: red - Gcg and Ins1 (assay MGI:6382865) and Ins2 (assay MGI:6382879); green - Ghrl (assay MGI:6382721).
Structure Level Pattern Image Note
TS23: pancreas Weak S2B weak / NS
Specimen 8A: embryonic day 15.5 (more )
Note: Double labeled: red - Gcg and Ins1 (assay MGI:6382865) and Ins2 (assay MGI:6382879); green - Sst (assay MGI:6382871).
Structure Level Pattern Image Note
TS23: pancreas Present 8A
Specimen 8B: embryonic day 15.5 (more )
Note: Double labeled: red - Gcg and Ins1 (assay MGI:6382865) and Ins2 (assay MGI:6382879); green - Ghrl (assay MGI:6382721).
Structure Level Pattern Image Note
TS23: pancreas Present 8B
Specimen 8C: embryonic day 15.5; Mafbm1Gsb/Mafbm1Gsb (more )
Note: Double labeled: red - Gcg and Ins1 (assay MGI:6382865) and Ins2 (assay MGI:6382879); green - Sst (assay MGI:6382871).
Structure Level Pattern Image Note
TS23: pancreas Weak 8C Reduction in number of expressing cells compared to wild type.
Specimen 8D: embryonic day 15.5; Mafbm1Gsb/Mafbm1Gsb (more )
Note: Double labeled: red - Gcg and Ins1 (assay MGI:6382865) and Ins2 (assay MGI:6382879); green - Ghrl (assay MGI:6382721).
Structure Level Pattern Image Note
TS23: pancreas Weak 8D Reduction in number of expressing cells compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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