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Gene Expression Data
Assay Details
Assay
Reference: J:108721 Nishimura W, et al., A switch from MafB to MafA expression accompanies differentiation to pancreatic beta-cells. Dev Biol. 2006 May 15;293(2):526-39
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6361020
Gene symbol: Nkx6-1
Gene name: NK6 homeobox 1
Antibody: anti-Nkx6.1
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to Alexa Fluor 488
Results
Specimen 7B: embryonic day 15.5 (more )
Note: Triple labeled: green - Nkx6-1; red - Ins1 (assay MGI:6361010) and Ins2 (assay MGI:6361013); blue - DAPI.
Structure Level Pattern Image Note
TS23: endocrine pancreas Present Regionally restricted 7B Not all Nkx6-1-expressing cells express insulin. More Nkx6.1-expressing cells than cells that express Mafb.
Specimen 7E: embryonic day 15.5 (more )
Note: Triple labeled: green - Nkx6-1; red - glucagon (Gcg; assay MGI:6361016); blue - DAPI.
Structure Level Pattern Image Note
TS23: endocrine pancreas Present Regionally restricted 7E
Specimen 8A: embryonic day 15.5 (more )
Note: Triple labeled: green - Nkx6-1; red - Glut2 (Slc2a2; assay MGI:6361021); blue - DAPI.
Structure Level Pattern Image Note
TS23: endocrine pancreas Present Regionally restricted 8A
Specimen 9A: embryonic day 15.5 (more )
Note: Double labeled: green - Nkx6-1; red - Ki-67 (Mki67; assay MGI:6361022).
Structure Level Pattern Image Note
TS23: endocrine pancreas Present Regionally restricted 9A
Specimen 9E: postnatal day 14 (more )
Note: Double labeled: green - Nkx6-1; red - Ki-67 (Mki67; assay MGI:6361022).
Structure Level Pattern Image Note
TS28: endocrine pancreas Present Regionally restricted 9E
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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