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Mirlet7b Gene Detail
Summary
  • Symbol
    Mirlet7b
  • Name
    microRNA let7b
  • Synonyms
    Mirnlet7b, mmu-let-7b
Location &
Maps
more
  • Sequence Map
    Chr15:85591520-85591604 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 40.42 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    133 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676794
 miRNA gene Chr15:85591520-85591604 (+)
129S1/SvImJ ENSMUSG00200035747
 miRNA gene Chr15:82717762-82717846 (+)
A/J ENSMUSG00195020974
 miRNA gene Chr15:82644219-82644303 (+)
AKR/J ENSMUSG00220030313
 miRNA gene Chr15:82697438-82697522 (+)
BALB/cJ ENSMUSG00180015059
 miRNA gene Chr15:82520929-82521013 (+)
C3H/HeJ ENSMUSG00175028088
 miRNA gene Chr15:82831819-82831903 (+)
C57BL/6NJ ENSMUSG00215029624
 miRNA gene Chr15:82610866-82610950 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007451
 miRNA gene Chr15:79694516-79694600 (+)
CAST/EiJ ENSTCUG00005031859
 miRNA gene Chr15:82110154-82110238 (+)
CBA/J ENSMUSG00210013272
 miRNA gene Chr15:82606694-82606778 (+)
DBA/2J ENSMUSG00185022497
 miRNA gene Chr15:82632488-82632572 (+)
FVB/NJ ENSMUSG00205035996
 miRNA gene Chr15:82392833-82392917 (+)
JF1/MsJ ENSUMUG00000043582
 miRNA gene Chr15:82150796-82150880 (+)
LP/J no annotation
NOD/ShiLtJ ENSMUSG00190029300
 miRNA gene Chr15:82630195-82630279 (+)
NZO/HlLtJ no annotation
PWK/PhJ ENSLUMG00010035957
 miRNA gene Chr15:82357655-82357739 (+)
SPRET/EiJ ENSMSPG00010015105
 miRNA gene Chr15:84014992-84015076 (+)
WSB/EiJ ENSIUOG00005011396
 miRNA gene Chr15:82697749-82697833 (+)



Homology
more
  • Human Ortholog
    MIRLET7B, microRNA let-7b
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIRLET7B, microRNA let-7b
  • Synonyms
    hsa-let-7b, let-7b, LET7B, MIRNLET7B
  • Links
    NCBI Gene ID: 406884

  • Chr Location
    chr22:46113686-46113768 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    21 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Radiation induced
    2
  • Genomic Mutations
    3 involving Mirlet7b
  • Find Mice (IMSR)
    2 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    617
  • Tissues
    15
  • cDNA Data
    3
  • Literature Summary
    24
Sequences &
Gene Models
less
  • All Sequences
    24
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 387245 NCBI Gene Model | MGI Sequence Detail 85 C57BL/6J ±  kb
transcript NR_029727 RefSeq | MGI Sequence Detail 85 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 10
    cDNA 3
    Primer pair 4
    Other 3

    Microarray probesets 1
Other Database
Links
less
miRBase MI0000558
References
more
  • Summaries
    All 83
    Developmental Gene Expression 24
    Diseases 1
    Gene Ontology 10
    Phenotypes 21
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory