About   Help   FAQ
Mirc31 Complex/Cluster/Region Detail
Summary
  • Symbol
    Mirc31
  • Name
    microRNA cluster 31, including Mirlet7c-2 through Mirlet7b
  • Feature Type
    complex/cluster/region
  • IDs
    MGI:5315466
  • Cluster Members
    Mirlet7c-2, Mirlet7b (2 members)
Location &
Maps
less
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 15, Syntenic
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 3 alleles in 3 genetic backgrounds
    2 phenotypes from multigenic genotypes
    25 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele of this cluster are viable.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    3
  • Tissues
    3
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    Molecular
    Reagents
    less
    • All nucleic 1
      Primer pair 1
    Other Database
    Links
    less
    miRBase MI0000558, MI0000560
    References
    more
    • Summaries
      All 28
      Developmental Gene Expression 1
      Phenotypes 25
    • Earliest
      J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
    • Latest
      J:358024 Erice PA, et al., Downregulation of Mirlet7 miRNA family promotes Tc17 differentiation and emphysema via de-repression of RORgammat. Elife. 2024 May 9;13
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    01/13/2026
    MGI 6.24     		The Jackson Laboratory