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Cyp2d34 Gene Detail
Summary
  • Symbol
    Cyp2d34
  • Name
    cytochrome P450, family 2, subfamily d, polypeptide 34
  • Synonyms
    MGC:18824
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385022
    NCBI Gene: 223706
  • Member of
    Cyp2d cluster
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:82500166-82505147 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 38.66 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    283 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385022
 protein coding gene Chr15:82500164-82505157 (-)
129S1/SvImJ ENSMUSG00200051157
 protein coding gene Chr15:79613891-79618876 (-)
A/J ENSMUSG00195045536
 protein coding gene Chr15:79545547-79550528 (-)
AKR/J ENSMUSG00220051195
 protein coding gene Chr15:79588726-79593715 (-)
BALB/cJ ENSMUSG00180044351
 protein coding gene Chr15:79422475-79427460 (-)
C3H/HeJ ENSMUSG00175045556
 protein coding gene Chr15:79733447-79738432 (-)
C57BL/6NJ ENSMUSG00215048918
 protein coding gene Chr15:79517753-79522734 (-)
CAROLI/EiJ no annotation
CAST/EiJ ENSTCUG00005045977
 protein coding gene Chr15:79002208-79007152 (-)
CBA/J ENSMUSG00210048533
 protein coding gene Chr15:79508535-79513520 (-)
DBA/2J ENSMUSG00185046811
 protein coding gene Chr15:79532345-79537335 (-)
FVB/NJ ENSMUSG00205040917
 protein coding gene Chr15:79276177-79281147 (-)
JF1/MsJ ENSUMUG00000033652
 protein coding gene Chr15:79072851-79077854 (-)
LP/J ENSMUSG00230040469
 protein coding gene Chr15:82854252-82859229 (-)
NOD/ShiLtJ ENSMUSG00190033001
 protein coding gene Chr15:79525627-79530612 (-)
NZO/HlLtJ ENSMUSG00225048198
 protein coding gene Chr15:83192811-83197796 (-)
PWK/PhJ ENSLUMG00010047025
 protein coding gene Chr15:79283253-79288235 (-)
SPRET/EiJ ENSMSPG00010043976
 protein coding gene Chr15:80948318-80953196 (-)
WSB/EiJ ENSIUOG00005042000
 protein coding gene Chr15:79596975-79601961 (-)



Homology
more
  • Human Ortholog
    CYP2D6, cytochrome P450 family 2 subfamily D member 6 (gene/pseudogene)
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CYP2D6, cytochrome P450 family 2 subfamily D member 6 (gene/pseudogene)
  • Synonyms
    CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450C2D, P450-DB1, P450DB1
  • Links
    NCBI Gene ID: 1565
    UniProt: P10635

  • Chr Location
    22q13.2; chr22:42125962-42131236 (-)  GRCh38
  • Human Ortholog
    CYP2D7, cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)
  • Synonyms
    CYP2D, CYP2D@, CYP2D7AP, CYP2D7P, CYP2D7P1, P450C2D, P450DB1, RNA40057
  • Links
    NCBI Gene ID: 1564
    UniProt: A0A087X1C5

  • Chr Location
    22q13.2; chr22:42139576-42149455 (-)  GRCh38
Human Diseases
more
  • Diseases
    9 with human CYP2D6 associations

Human Disease Mouse Models
      
IDs
IDs
IDs
IDs
IDs
IDs
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    25 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    27
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    13
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000094559 Ensembl Gene Model | MGI Sequence Detail 4982 C57BL/6J ±  kb
transcript ENSMUST00000109515 Ensembl | MGI Sequence Detail 1660 Not Applicable  
polypeptide ENSMUSP00000105141 Ensembl | MGI Sequence Detail 504 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 2
References
more
  • Summaries
    All 47
    Diseases 1
    Gene Ontology 8
    Phenotypes 25
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory