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Slc26a7 Gene Detail
Summary
  • Symbol
    Slc26a7
  • Name
    solute carrier family 26, member 7
  • Synonyms
    MGC:30955
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384791
    NCBI Gene: 208890
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:14502430-14621805 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 6.24 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    3497 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2384791
 protein coding gene Chr4:14502430-14621946 (-)
129S1/SvImJ ENSMUSG00200000833
 protein coding gene Chr4:11150336-11269907 (-)
A/J ENSMUSG00195015997
 protein coding gene Chr4:11590564-11710837 (-)
AKR/J ENSMUSG00220001236
 protein coding gene Chr4:11335491-11455072 (-)
BALB/cJ ENSMUSG00180001846
 protein coding gene Chr4:11098030-11217593 (-)
C3H/HeJ ENSMUSG00175018221
 protein coding gene Chr4:11617722-11737271 (-)
C57BL/6NJ ENSMUSG00215008446
 protein coding gene Chr4:11254062-11373615 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025820
 protein coding gene Chr4:10341518-10463239 (-)
CAST/EiJ ENSTCUG00005016371
 protein coding gene Chr4:11276833-11398394 (-)
CBA/J ENSMUSG00210001479
 protein coding gene Chr4:11355440-11474969 (-)
DBA/2J ENSMUSG00185001065
 protein coding gene Chr4:11465685-11585244 (-)
FVB/NJ ENSMUSG00205001727
 protein coding gene Chr4:11014060-11133612 (-)
JF1/MsJ ENSUMUG00000001155
 protein coding gene Chr4:11516244-11645269 (-)
LP/J ENSMUSG00230000904
 protein coding gene Chr4:14647270-14766828 (-)
NOD/ShiLtJ ENSMUSG00190024725
 protein coding gene Chr4:11212138-11332444 (-)
NZO/HlLtJ ENSMUSG00225007736
 protein coding gene Chr4:18639947-18759494 (-)
PWK/PhJ ENSLUMG00010001785
 protein coding gene Chr4:10969922-11083998 (-)
SPRET/EiJ ENSMSPG00010013014
 protein coding gene Chr4:11415670-11533485 (-)
WSB/EiJ ENSIUOG00005007936
 protein coding gene Chr4:11015150-11135536 (-)



Homology
more
  • Human Ortholog
    SLC26A7, solute carrier family 26 member 7
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC26A7, solute carrier family 26 member 7
  • Synonyms
    SUT2
  • Links
    NCBI Gene ID: 115111
    UniProt: Q8TE54

  • Chr Location
    8q21.3; chr8:91209494-91398155 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with Slc26a7 mouse models

Human Disease Mouse Models
      
IDs
 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice deficient for this marker have a reduce arterial pH and reduced serum bicarbonate. Urine is more concentrated and has an elevated pH.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    73
  • GO References
    17
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    937
  • Tissues
    139
  • cDNA Data
    5
  • Literature Summary
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000040569 Ensembl Gene Model | MGI Sequence Detail 119376 C57BL/6J ±  kb
    transcript ENSMUST00000042221 Ensembl | MGI Sequence Detail 5165 Not Applicable  
    polypeptide ENSMUSP00000041789 Ensembl | MGI Sequence Detail 656 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 5
      Primer pair 3
      Other 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 45
      Developmental Gene Expression 6
      Diseases 1
      Gene Ontology 17
      Phenotypes 10
    • Earliest
      J:131477 Petrovic S, et al., Identification of a basolateral Cl-/HCO3- exchanger specific to gastric parietal cells. Am J Physiol Gastrointest Liver Physiol. 2003 Jun;284(6):G1093-103
    • Latest
      J:326785 Yamaguchi N, et al., The iodide transporter Slc26a7 impacts thyroid function more strongly than Slc26a4 in mice. Sci Rep. 2022 Jul 4;12(1):11259
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory