About   Help   FAQ
Nkapd1 Gene Detail
Summary
  • Symbol
    Nkapd1
  • Name
    NKAP domain containing 1
  • Synonyms
    Ahed, AU019823, LOC270156
  • Feature Type
    protein coding gene
  • IDs
    MGI:2143205
    NCBI Gene: 270156
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:50516542-50528567 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 27.75 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    251 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2143205
 protein coding gene Chr9:50516540-50528764 (-)
129S1/SvImJ ENSMUSG00200017768
 protein coding gene Chr9:47687880-47700097 (-)
A/J ENSMUSG00195019453
 protein coding gene Chr9:47371169-47383397 (-)
AKR/J ENSMUSG00220034590
 protein coding gene Chr9:47461648-47473872 (-)
BALB/cJ ENSMUSG00180029190
 protein coding gene Chr9:47482568-47494792 (-)
C3H/HeJ ENSMUSG00175014630
 protein coding gene Chr9:47494601-47506825 (-)
C57BL/6NJ ENSMUSG00215016904
 protein coding gene Chr9:47443961-47456185 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032189
 protein coding gene Chr9:47457155-47470500 (-)
CAST/EiJ ENSTCUG00005014746
 protein coding gene Chr9:47408531-47420762 (-)
CBA/J ENSMUSG00210016350
 protein coding gene Chr9:47560536-47572765 (-)
DBA/2J ENSMUSG00185009503
 protein coding gene Chr9:47609063-47621287 (-)
FVB/NJ ENSMUSG00205031061
 protein coding gene Chr9:47836072-47848292 (-)
JF1/MsJ ENSUMUG00000029915
 protein coding gene Chr9:47664460-47676673 (-)
LP/J ENSMUSG00230040277
 protein coding gene Chr9:47903663-47915880 (-)
NOD/ShiLtJ ENSMUSG00190017886
 protein coding gene Chr9:47689154-47701378 (-)
NZO/HlLtJ ENSMUSG00225043569
 protein coding gene Chr9:47864927-47877151 (-)
PWK/PhJ ENSLUMG00010020037
 protein coding gene Chr9:47629318-47641542 (-)
SPRET/EiJ ENSMSPG00010010281
 protein coding gene Chr9:48443324-48455482 (-)
WSB/EiJ ENSIUOG00005017809
 protein coding gene Chr9:47103920-47116169 (-)



Homology
more
  • Human Ortholog
    NKAPD1, NKAP domain containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NKAPD1, NKAP domain containing 1
  • Synonyms
    Ahed, C11orf57
  • Links
    NCBI Gene ID: 55216
    UniProt: Q6ZUT1

  • Chr Location
    11q23.1; chr11:112074086-112085152 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    41 phenotypes from 2 alleles in 5 genetic backgrounds
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    8
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 270156 NCBI Gene Model | MGI Sequence Detail 12026 C57BL/6J ±  kb
    transcript NM_001360340 RefSeq | MGI Sequence Detail 3687 C57BL/6  
    polypeptide NP_997614 RefSeq | MGI Sequence Detail 292 C57BL/6  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      5 Sequences
    • InterPro Domains
      IPR043407 Nkap domain containing 1
    Molecular
    Reagents
    less
    • All nucleic 8
      cDNA 8

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2685485, MGI:6156356
    References
    more
    • Summaries
      All 31
      Gene Ontology 2
      Phenotypes 12
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:372082 Takaishi M, et al., A Newly Identified Spliceosomal Protein AHED Is Essential for Homeostasis of the Epidermis. J Invest Dermatol. 2025 Sep;145(9):2261-2271.e15
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory