Nkapd1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nkapd1
NKAP domain containing 1
MGI:2143205

41 phenotypes from 2 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nkapd1^em1(IMPC)Mbp/Nkapd1⁺ C57BL/6N-Nkapd1^em1(IMPC)Mbp/MbpMmucd	abnormal kidney morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal visceral yolk sac morphology	J:211773
	abnormal vitelline vasculature morphology	J:211773
	decreased prepulse inhibition	J:211773
	increased freezing behavior	J:211773
	small kidney	J:211773
Nkapd1^em1(IMPC)Mbp/Nkapd1^em1(IMPC)Mbp C57BL/6N-Nkapd1^em1(IMPC)Mbp/MbpMmucd	embryonic lethality prior to organogenesis	J:211773
	preweaning lethality, complete penetrance	J:211773
Nkapd1^tm1.1Tak/Nkapd1⁺ involves: C57BL/6J	no abnormal phenotype detected	J:350073
Nkapd1^tm1.1Tak/Nkapd1^tm1.1Tak involves: C57BL/6J	no abnormal phenotype detected	J:350073
Nkapd1^tm1.1Tak/Nkapd1^tm1.1Tak Commd10^{Tg(Vav1-icre)A2Kio}/Commd10⁺ involves: C57BL/6J * C57BL/10 * CBA/Ca	abnormal B cell differentiation	J:350073
	abnormal cell cycle	J:350073
	abnormal definitive hematopoiesis	J:350073
	abnormal erythroblast number	J:350073
	abnormal erythroid lineage cell morphology	J:350073
	abnormal fetal liver hematopoietic progenitor cell morphology	J:350073
	abnormal hematopoietic precursor cell morphology	J:350073
	abnormal proerythroblast morphology	J:350073
	anemia	J:350073
	decreased common lymphocyte progenitor cell number	J:350073
	decreased erythroid progenitor cell number	J:350073
	increased apoptosis	J:350073
	increased hematopoietic stem cell number	J:350073
	lethality during fetal growth through weaning, complete penetrance	J:350073
	perinatal lethality, complete penetrance	J:350073
	small liver	J:350073
	subcutaneous edema	J:350073
Nkapd1^tm1.1Tak/Nkapd1^tm1.1Tak Gt(ROSA)26Sor^{tm1(cre/ERT2)Tyj}/Gt(ROSA)26Sor⁺ involves: 129S4/SvJae * C57BL/6 * C57BL/6J	abnormal definitive hematopoiesis	J:350073
	abnormal esophageal epithelium morphology	J:350073
	abnormal intestinal mucosa morphology	J:350073
	abnormal tongue epithelium morphology	J:350073
	decreased body weight	J:350073
	decreased bone marrow cell number	J:350073
	decreased erythroid progenitor cell number	J:350073
	decreased leukocyte cell number	J:350073
	decreased lymphocyte cell number	J:350073
	epidermal atrophy	J:350073
	increased hematopoietic stem cell number	J:350073
	increased megakaryocyte-erythroid progenitor cell number	J:350073
	postnatal lethality	J:350073
	premature death	J:350073
	small intestinal inflammation	J:350073
Nkapd1^tm1.1Tak/Nkapd1^tm1.1Tak Tg(Tek-cre)1Ywa/0 involves: C57BL/6 * C57BL/6J * SJL	normal hematopoietic system phenotype	J:350073
	lethality throughout fetal growth and development, complete penetrance	J:350073

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